Milli-Q® IPAKKITEX Purification Cartridge Kit for Elix® Feed Water
| Brand | Milli-Q |
|---|---|
| Origin | France |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Status | Imported |
| Model | IPAKKITEX |
| Purity Grade | ASTM Type I / ISO 3696 Grade 1 / CLSI EP25-A2 Compliant |
| Resistivity | 18.2 MΩ·cm @ 25 °C |
| Heavy Metals & Soluble Silica | <0.1 ppb |
| Total Organic Carbon (TOC) | <5 ppb |
| Microbial Count / Endotoxins | <0.001 EU/mL |
| Particles (>0.1 µm) | <1 particles/mL |
Overview
The Milli-Q® IPAKKITEX Purification Cartridge Kit is a factory-assembled, pre-validated dual-cartridge system engineered exclusively for integration with Elix® water purification platforms. It serves as the final polishing stage in a multi-step ultrapure water production chain—receiving pretreated feed water from Elix® systems and delivering Type I ultrapure water compliant with ASTM D1193, ISO 3696, and CLSI EP25-A2 standards. The kit comprises two synergistically designed cartridges: the IPAK Meta® cartridge, optimized for residual ion removal, and the IPAK Quanta® cartridge, dedicated to organic contaminant reduction and endotoxin control. This configuration leverages Couette-flow–enhanced contact kinetics and high-capacity, low-leaching media to ensure consistent resistivity ≥18.2 MΩ·cm at 25 °C, TOC ≤5 ppb, and endotoxin levels below 0.001 EU/mL—critical thresholds for LC-MS, ICP-MS, cell culture, and molecular biology workflows.
Key Features
- Pre-assembled, serialized, and lot-tested dual-cartridge architecture—eliminates field alignment errors and ensures reproducible installation.
- IPAK Meta® cartridge containing Jetpore® macroporous mixed-bed ion exchange resin and IQo™ proprietary ion exchange media for sub-ppt-level cation/anion scavenging.
- IPAK Quanta® cartridge integrating pharmaceutical-grade synthetic activated carbon with controlled pore distribution and low ash content to adsorb trace organics, chlorine derivatives, and THMs without leaching.
- Endotoxin-retentive membrane layer integrated into the Quanta® cartridge housing, validated per USP and EP 2.6.14 protocols.
- Cartridge housings constructed from Class VI-certified polypropylene with zero extractables; fully compatible with Milli-Q® system pressure and flow specifications (max. 2.5 bar, 2.0 L/min).
- Integrated RFID tag enabling automatic recognition, usage tracking, and firmware-synchronized lifetime monitoring within Milli-Q® Connect-enabled platforms.
Sample Compatibility & Compliance
The IPAKKITEX kit is validated only for use with Elix® series feed water (conductivity ≤5 µS/cm, TOC ≤50 ppb, silica ≤0.1 mg/L). It is not intended for direct municipal or well water input. All components meet USP , ISO 10993-5, and EC 1935/2004 material safety requirements. System-level compliance includes full traceability for GLP/GMP environments: each cartridge batch carries full CoA documentation, including ion chromatography chromatograms, TOC validation reports, and bacterial retention test data (log reduction value ≥7 for Pseudomonas diminuta). The entire assembly supports 21 CFR Part 11-compliant audit trails when used with Milli-Q® Integral or Advantage A10 systems equipped with Q-Connect software.
Software & Data Management
When deployed on Milli-Q® systems with Q-Connect connectivity, the IPAKKITEX kit enables real-time consumable lifecycle management. The embedded RFID chip logs cumulative volume processed, inlet/outlet conductivity trends, and temperature-compensated resistivity decay profiles. Users can configure alerts for remaining service life (based on volume or time), initiate remote calibration verification, and export CSV-formatted usage logs—including timestamps, operator IDs, and system event flags—for inclusion in electronic lab notebooks (ELN) or LIMS. Historical performance data is retained for ≥12 months and aligns with ALCOA+ data integrity principles.
Applications
This purification kit is specified for applications demanding the highest water purity assurance: preparation of mobile phases for UHPLC and HPLC-MS; diluent formulation for trace elemental analysis (ICP-OES, ICP-MS); buffer preparation for electrophysiology and stem cell expansion; reagent-grade water for qPCR master mixes and CRISPR-Cas9 editing workflows; and rinsing of quartz cuvettes and optical substrates in UV-Vis and fluorescence spectroscopy. Its consistent low endotoxin and particle profile also supports ISO 14644-1 Class 5 cleanroom maintenance protocols.
FAQ
Can IPAKKITEX be used with non-Milli-Q® Elix® systems?
No. It is mechanically and electronically certified only for Elix® 10, 20, and 30 platforms with Milli-Q® interface firmware v4.2 or later.
What is the recommended replacement interval?
Under typical laboratory conditions (≤100 L/day, feed water meeting Elix® spec), replacement is advised every 6 months or after 1,500 L—whichever occurs first. Volume-based alerts are automatically triggered via Q-Connect.
Does the kit require system recalibration upon installation?
No. Factory calibration and RFID handshake eliminate manual calibration; resistivity and TOC sensors auto-validate during first 30 minutes of operation.
Is the IPAKKITEX kit compliant with ISO/IEC 17025 accreditation requirements?
Yes. Full metrological traceability, uncertainty budgets, and inter-laboratory validation reports are available upon request from Merck’s Technical Documentation Center (TDC).
