Rainin Pipet-Lite XLS+ Single-Channel Manual Pipette

Overview

The Rainin Pipet-Lite XLS+ Single-Channel Manual Pipette is an ergonomically engineered precision liquid handling instrument designed for high-frequency, low-volume applications in regulated and research-intensive laboratories. Operating on positive displacement mechanics with a stainless-steel piston and PTFE-coated seals, it delivers consistent volumetric delivery across its full 0.1–2 µL range. Its design integrates mechanical innovation—including magnetic-assisted plunger actuation and a patented LTS™ (Low Retention Tip) LightTouch™ tip ejection system—to minimize operator-induced variability and reduce biomechanical stress during repetitive pipetting tasks. As part of Rainin’s XLS+ platform, this pipette meets the functional and compliance requirements of ISO 8655-2 (volumetric performance), ISO 8655-5 (calibration), and supports audit readiness under FDA 21 CFR Part 11 and EU Annex 11 when paired with compatible RFID readers and validated software.

Key Features

• Ergonomic architecture featuring a contoured soft-grip handle, ultra-low spring force (≤1.2 N for aspiration at 2 µL), and magnetic-assisted plunger return—reducing peak hand force by up to 45% compared to conventional manual pipettes.
• LTS™ LightTouch™ tip attachment system ensures consistent, low-force tip seating and near-zero tip wobble, minimizing dead volume and improving reproducibility at sub-microliter volumes.
• Autoclavable liquid end assembly—including piston seal, O-rings, and polymer tip ejector—validated for ≥20 cycles at 121°C, 1 bar, without degradation in accuracy or tactile response.
• Integrated RFID chip (ISO 15693 compliant) stores unique serial number, calibration history, service logs, and user-defined metadata; readable via Rainin ProFlow™ or third-party RFID-enabled lab inventory systems.
• Glove-compatible volume adjustment dial with anti-slip knurling and mechanical lock prevents accidental volume drift during operation or transport.
• Modular construction enables field-replaceable components (tip ejector, sleeve, seal kit) without specialized tools—supporting rapid maintenance and extended service life.

Sample Compatibility & Compliance

The Pipet-Lite XLS+ is compatible with all standard conical and LTS™-certified low-retention tips (0.1–10 µL nominal capacity). Its optimized airflow dynamics and minimal internal dead volume (<0.5 µL) ensure reliable handling of viscous, volatile, or surfactant-laden solutions—including DMSO, glycerol/water mixtures, and PCR master mixes—without carryover or evaporation artifacts. The device conforms to ISO 8655-2:2022 for gravimetric accuracy and precision testing protocols, with documented performance verified at three volume points (0.2 µL, 1.0 µL, and 2.0 µL) per ISO 8655-5:2022. For quality-critical environments, it supports GLP/GMP workflows through traceable calibration records, electronic audit trails (when used with Rainin Calibrate™ software), and integration into laboratory information management systems (LIMS) via CSV or XML export.

Software & Data Management

When connected to a Rainin ProFlow™ RFID reader and Calibrate™ desktop software (Windows/macOS), the Pipet-Lite XLS+ enables automated calibration documentation, version-controlled firmware updates, and customizable service scheduling. Calibration data—including date, technician ID, environmental conditions (temperature/humidity), and measured deviation values—is encrypted and stored both locally and optionally synced to cloud-based instrument management dashboards. All electronic records comply with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) and support 21 CFR Part 11-compliant electronic signatures when deployed with appropriate validation packages.

Applications

This pipette is routinely deployed in quantitative molecular biology workflows requiring nanoliter-level fidelity: qPCR assay setup, CRISPR guide RNA complex assembly, single-cell lysate transfer, microfluidic device priming, and high-throughput screening plate replication. Its low-volume precision makes it suitable for standards preparation in LC-MS method development, enzymatic activity assays with limited substrate availability, and QC testing of diagnostic reagents where coefficient of variation (CV) <1.5% at 2 µL is required. In clinical diagnostics labs, it supports ISO 15189-aligned pre-analytical sample dilution protocols and proficiency testing programs demanding inter-operator reproducibility.

FAQ

Is the Pipet-Lite XLS+ compatible with non-LTS tips?
Yes, it can accept universal conical tips via optional adapter sleeves, though LTS™ tip use is strongly recommended to maintain specified accuracy and repeatability.
What is the recommended recalibration interval?
Per ISO 8655-5, recalibration is advised every 3–6 months depending on usage frequency and criticality of application; daily verification using gravimetric checks is recommended for GLP/GMP environments.
Can the RFID chip be rewritten or erased?
No—the chip is write-once for core identity and calibration events; subsequent entries are appended as immutable timestamped records to preserve data integrity.
Does autoclaving affect the magnetic-assist mechanism?
No—magnetic components are thermally stable up to 150°C and retain full functionality after repeated autoclave cycles.
How is traceability maintained if the pipette is loaned between labs?
RFID data remains associated with the physical unit regardless of location; access control and user permissions in Calibrate™ software ensure role-based visibility and change logging.