RWD R34001-14 Vascular Clip Applier

Overview

The RWD R34001-14 Vascular Clip Applier is a precision-engineered surgical instrument designed for reliable, repeatable application of small vascular clips during microsurgical and preclinical research procedures. Engineered for use in rodent and small-animal models, this applier operates on a mechanical compression principle—transferring hand-applied force through a lever-actuated mechanism to uniformly close standardized titanium or stainless-steel vascular clips (e.g., 3.5 mm and 5 mm standard clip sizes). Its ergonomic design minimizes operator fatigue during prolonged procedures, while its fine-tuned jaw alignment ensures consistent clip deployment without slippage or deformation. The device is intended for single-user, reusable operation under sterile conditions and complies with general biocompatibility and mechanical safety expectations for Class I non-sterile surgical instruments per ISO 13485–aligned manufacturing practices.

Key Features

• Ergonomic, lightweight aluminum alloy body with textured non-slip grip surface for enhanced tactile control during delicate vascular manipulations
• Adjustable clip retention mechanism compatible with standard 3.5 mm and 5 mm vascular clips (including RWD R34000-series and generic equivalents)
• Precision-machined tungsten-carbide-coated jaws for high wear resistance and long-term dimensional stability
• Integrated spring-return action for rapid reset between clip applications, reducing procedural downtime
• Autoclavable up to 134 °C (273 °F) for steam sterilization; validated for ≥500 cycles without performance degradation
• Calibration-free mechanical design—no electronic components, batteries, or software dependencies

Sample Compatibility & Compliance

The R34001-14 is validated for use with commercially available small-animal vascular clips conforming to ASTM F2811 standards for metallic surgical clips. It supports both straight and angled clip configurations when used with appropriate clip-loading accessories. While the applier itself is classified as a Class I medical device under Chinese NMPA regulations (Registration No. GD2022XXXXX), it is supplied as a research-use-only (RUO) instrument outside China and does not carry CE marking or FDA 510(k) clearance. Users are responsible for verifying local regulatory status and validating clip-applier compatibility within their specific experimental protocols. The device meets ISO 10993-5 cytotoxicity requirements for metallic components in contact with biological tissue.

Software & Data Management

This is a fully mechanical, non-electronic instrument with no embedded firmware, connectivity interfaces, or digital data output capabilities. As such, it does not require software installation, calibration records, or audit trails. All usage parameters—including clip type, batch number, sterilization cycle log, and operator ID—are documented manually in laboratory notebooks or electronic lab management systems (ELN/LIMS) per GLP-compliant study protocols. For traceability, each unit bears a permanent laser-etched serial number compatible with institutional asset-tracking workflows.

Applications

• Microvascular surgery in rodent models, including carotid artery ligation, renal pedicle occlusion, and cerebral vessel clipping
• Preclinical pharmacology studies requiring transient or permanent vascular occlusion (e.g., ischemia-reperfusion injury models)
• Neurosurgical training platforms where consistent clip placement and closure force are critical for skill acquisition
• Cardiovascular device evaluation studies involving clip-based anastomosis or embolization support
• Teaching laboratories focused on fundamental microsurgical technique development and hemostasis assessment

FAQ

Is the R34001-14 autoclavable?
Yes—fully autoclavable at 134 °C for 5 minutes using standard gravity or prevacuum cycles. Verify compatibility with your facility’s sterilization validation protocol.
What clip sizes does it support out of the box?
The applier is optimized for 3.5 mm and 5 mm standard-length vascular clips. Clip adapters for other dimensions are available separately under part numbers R34001-ADP-3 and R34001-ADP-5.
Does RWD provide clip compatibility documentation?
Yes—technical bulletins listing tested clip brands (e.g., Fine Science Tools, Roboz, World Precision Instruments) and dimensional tolerances are available upon request from RWD Technical Support.
Can this applier be used in sterile human surgical settings?
No—it is designated RUO (Research Use Only) and not certified for clinical human use under FDA, MDR, or PMDA frameworks.
How often should maintenance be performed?
Inspect jaws and pivot points before each use; clean with enzymatic detergent and rinse thoroughly after every procedure. Lubrication is not required due to self-lubricating polymer bushings.