Shanghai Yarong RE-52AA Rotary Evaporator
| Brand | Jinye |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Region of Origin | Domestic (China) |
| Model | RE-52AA |
| Capacity Range | 50–2000 mL |
| Rotational Speed | 0–150 rpm |
| Temperature Control Range | Ambient to 99 °C |
| Temperature Control Accuracy | ±1 °C |
| Condenser Cooling Surface Area | 0.12 m² |
Overview
The Shanghai Yarong RE-52AA Rotary Evaporator is a benchtop vacuum distillation system engineered for reproducible solvent removal, concentration, and gentle sample recovery under reduced pressure. It operates on the principle of rotary evaporation—where a rotating flask increases the evaporative surface area while simultaneous application of heat (via water or oil bath) and vacuum lowers the boiling point of solvents. This enables efficient, low-temperature separation of thermolabile compounds commonly encountered in pharmaceutical R&D, natural product isolation, and synthetic chemistry workflows. Designed for routine laboratory use, the RE-52AA integrates digital control of rotation speed and bath temperature, vertical motorized lift for safe flask positioning, and an integrated top-entry condenser with standardized 24/40 ground-glass joints and M32 quick-release couplings for rapid assembly and cleaning.
Key Features
- Digital dual-display interface showing real-time rotational speed (0–150 rpm) and heating bath temperature (ambient to 99 °C), with ±1 °C thermal regulation stability
- Motor-driven vertical lift mechanism enabling precise, hands-free adjustment of the evaporation flask relative to the heating bath—reducing operator exposure to hot surfaces and vacuum hazards
- Top-entry vertical condenser with high-efficiency cooling surface area of 0.12 m², optimized for condensate reflux under moderate vacuum (typically 10–100 mbar)
- Standardized 24/40 tapered glassware interface and M32 stainless-steel locking nut for secure, leak-tight connections and compatibility with common lab-grade rotary evaporation accessories
- Robust aluminum alloy mainframe with corrosion-resistant coating and reinforced support column for long-term mechanical stability during continuous operation
- Integrated vacuum seal design at the rotary joint and vapor path to minimize leakage and maintain consistent vacuum integrity across extended runs
Sample Compatibility & Compliance
The RE-52AA accommodates standard round-bottom flasks ranging from 50 mL to 2000 mL, supporting both small-scale screening and mid-scale preparative work. Its modular glass train allows seamless integration with external vacuum pumps (e.g., diaphragm or scroll types), chillers, and cold traps. While not certified to ISO/IEC 17025 or FDA 21 CFR Part 11 out-of-the-box, the instrument’s mechanical design and material traceability (borosilicate 3.3 glass, PTFE-sealed joints, stainless-steel hardware) align with general Good Laboratory Practice (GLP) expectations for non-regulated research environments. Users performing GMP-aligned purification steps should validate system performance—including temperature uniformity, rotational consistency, and vacuum hold-down—per internal SOPs referencing ASTM E2654 or equivalent methodology.
Software & Data Management
The RE-52AA is a standalone analog-digital hybrid instrument with no embedded microprocessor-based data logging or network connectivity. All operational parameters are monitored via front-panel LED displays; no software installation, firmware updates, or computer interface is required. For laboratories requiring audit trails or electronic records, integration with external data acquisition systems (e.g., LabVIEW-compatible analog outputs or optional relay-triggered I/O modules) is feasible through third-party adapters. Manual parameter recording remains the default workflow—consistent with many legacy rotary evaporators deployed in academic and contract research settings where regulatory documentation relies on bound logbooks and handwritten annotations per GLP Annex 11 guidance.
Applications
- Solvent removal from reaction mixtures in organic synthesis and medicinal chemistry
- Concentration of heat-sensitive biomolecules (e.g., peptides, enzymes, plant extracts) without denaturation
- Recovery and recycling of high-purity solvents in fine chemical manufacturing
- Preparative isolation of active pharmaceutical ingredients (APIs) prior to crystallization or lyophilization
- Removal of residual solvents from polymer solutions and nanomaterial dispersions
- Parallel evaporation setup when paired with multi-position heating baths and vacuum manifolds
FAQ
What is the maximum recommended vacuum level for stable operation?
The RE-52AA performs optimally at vacuum levels between 10 and 100 mbar. Operation below 5 mbar may increase bumping risk and reduce condensation efficiency without specialized cold trap integration.
Is the heating bath compatible with silicone oil or only water?
Yes—the bath chamber accepts both water and silicone oil media. Oil extends the usable temperature range above 100 °C; however, the stated 99 °C upper limit reflects the controller’s calibrated range for aqueous operation.
Can the unit be used with non-standard flask sizes or custom glassware?
Only if the custom components conform to 24/40 taper geometry and M32 thread specifications. Deviations compromise vacuum integrity and thermal coupling.
Does the RE-52AA include a vacuum pump or chiller?
No—these are auxiliary components selected separately based on solvent volatility, throughput requirements, and facility infrastructure.
What maintenance intervals are recommended for long-term reliability?
Inspect PTFE seals and rotary joint lubrication every 200 operating hours; clean condenser coils and bath chamber after each solvent class change; verify temperature sensor calibration annually using NIST-traceable reference standards.
