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Shimadzu Used GC-MS System GCMS-QP2020 Quadrupole Mass Spectrometer

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Brand Shimadzu
Origin Japan
Model GCMS-QP2020
Mass Range 1–1000 u
Resolution 1000–2000 (FWHM)
Sensitivity >300:1 (S/N, full-scan, octafluoronaphthalene)
Scan Speed 15,000 u/sec
Ion Source Shielded high-efficiency electron ionization (EI) source with OD lens technology
Vacuum System Dual 200 L/sec turbomolecular pumps (ion source + quadrupole)
Maximum Column Flow 15 mL/min
Compliance FDA 21 CFR Part 11, GLP/GMP audit trail capable via GCMS Insight software

Overview

The Shimadzu Used GC-MS System GCMS-QP2020 is a high-performance quadrupole gas chromatography mass spectrometry instrument engineered for robust, high-throughput qualitative and quantitative analysis of volatile and semi-volatile organic compounds. It operates on the principle of electron ionization (EI) coupled with quadrupole mass filtering, enabling selective detection across a mass range of 1–1000 u. Designed and manufactured in Japan, the system integrates a shielded, fully inert ion source with patented Off-Deflection (OD) lens technology and low-noise signal processing electronics to minimize matrix interference and electronic background noise—critical for trace-level analysis in complex matrices. Its dual-turbopump vacuum architecture (200 L/sec each for ion source and quadrupole) ensures rapid pump-down (<30 min to operational vacuum), stable high-vacuum conditions under variable carrier gas flows (He, H2, or N2), and extended maintenance intervals—particularly advantageous in regulated QC laboratories and academic core facilities requiring long-term uptime and reproducibility.

Key Features

  • Shielded high-efficiency EI ion source with integrated OD lens optics for enhanced ion transmission and reduced chemical noise
  • Dual independent 200 L/sec turbomolecular pumping system enabling simultaneous operation of two capillary columns (Twin Line MS configuration) without sensitivity loss
  • Advanced Scanning Speed Protocol (ASSP™) — patented real-time ion acceleration algorithm that mitigates high-mass discrimination during ultra-fast scanning (up to 15,000 u/sec), preserving spectral fidelity and quantitative accuracy
  • Full-metal, precision-machined quadrupole mass analyzer with thermal stability optimized for long-term mass calibration retention
  • Ecology Mode functionality reducing standby power consumption by up to 36% and carrier gas usage during idle periods—validated per ISO 14040 life-cycle assessment methodology
  • Support for wide-bore capillary columns (up to 0.53 mm ID) with maximum column flow of 15 mL/min, facilitating large-volume injection (LVI) and headspace-GC/MS applications

Sample Compatibility & Compliance

The GCMS-QP2020 accommodates a broad spectrum of sample types—including environmental extracts (e.g., PAHs, PCBs, pesticides), food contaminants (mycotoxins, plasticizers), pharmaceutical impurities, metabolites from biofluids, and polymer additives—provided they are amenable to GC separation and EI ionization. The system meets key international regulatory requirements: its GCMS Insight software implements role-based user authentication, configurable audit trails, electronic signature support, and secure data archiving aligned with FDA 21 CFR Part 11, EU Annex 11, and Japan’s MHLW Ordinance No. 147. Instrument qualification documentation (IQ/OQ/PQ templates) and raw data integrity protocols conform to ISO/IEC 17025 and ASTM E2655 guidelines for method validation in accredited testing laboratories.

Software & Data Management

GCMS Insight is a unified, Windows-based platform supporting end-to-end workflow automation—from method development and acquisition control to library searching (NIST, Wiley, custom libraries), peak integration, quantitation (internal standard, external standard, standard addition), and report generation. It features embedded compound identification algorithms leveraging retention index matching and spectral deconvolution (AMDIS-compatible). All raw data files (.qgd) are stored in a structured, non-proprietary binary format with embedded metadata (instrument parameters, tuning logs, sequence information), ensuring long-term readability and interoperability with third-party chemometric tools. Audit trail records include timestamped entries for method edits, data reprocessing, user logins, and instrument state changes—fully exportable as PDF or CSV for internal review or regulatory submission.

Applications

This system is routinely deployed in environmental monitoring labs for EPA Method 8270D (semivolatiles) and 8082A (PCBs); in food safety testing for EU Commission Regulation (EU) No. 2021/2090 compliance; in pharmaceutical R&D for residual solvent analysis per ICH Q3C; and in clinical research for targeted metabolomics profiling (e.g., acylcarnitines, bile acids). Its fast-scanning capability supports comprehensive 2D-GC/MS (GC×GC/MS) workflows, while the Twin Line MS configuration enables parallel analysis of polar/non-polar analytes—ideal for screening unknowns in forensic toxicology or flavor chemistry. The system’s dynamic linear range (>5 orders of magnitude) and fg-level detection limits make it suitable for biomarker discovery in serum or urine following derivatization and solid-phase microextraction (SPME).

FAQ

Is this unit refurbished or certified pre-owned?
This is a professionally inspected, functionally verified used instrument with documented operational history. It does not carry Shimadzu factory refurbishment certification but includes full hardware diagnostics, vacuum integrity verification, and baseline EI tuning reports.
Does it support SIM mode and scheduled SIM transitions?
Yes—GCMS Insight supports both single-ion monitoring (SIM) and time-programmed SIM transitions with dwell times adjustable from 10 ms to 1 s, enabling high-sensitivity multi-analyte quantitation without sacrificing chromatographic resolution.
Can it be integrated into a LIMS environment?
Yes—the system exports ASCII-delimited result files (.txt) and structured XML reports compatible with major LIMS platforms. Optional OPC UA server add-on enables real-time status monitoring and remote start/stop commands.
What maintenance documentation is included?
The unit ships with original service manuals, GCMS Insight software installation media, and a summary of last performed preventive maintenance (including filament replacement date, detector cleaning log, and vacuum gauge calibration certificate).
Is hydrogen carrier gas operation validated for this model?
Yes—hydrogen compatibility is fully supported per Shimadzu Application Note AN190-04A, including optimized source temperature settings, collision gas optimization, and retention time stability validation across 100+ reference standards.

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