Shimadzu Online TOC-V CSH Total Organic Carbon Analyzer (Refurbished)

Overview

The Shimadzu Online TOC-V CSH Total Organic Carbon Analyzer is a high-sensitivity, continuous-flow analytical system engineered for precise quantification of total carbon (TC), inorganic carbon (IC), and total organic carbon (TOC) in aqueous matrices. It employs high-temperature catalytic combustion (680 °C) coupled with non-dispersive infrared (NDIR) detection—a reference-grade methodology validated by JIS K 0102, ISO 8245, ASTM D7573, and pharmacopeial standards including USP and EP 2.2.44. Unlike benchtop TOC systems requiring manual injection, the TOC-V CSH is configured for true online operation: it integrates seamlessly with process streams or multi-point sampling networks via its built-in flow cell and optional OCT-1 eight-channel autosampler. This configuration supports unattended, real-time monitoring of ultra-pure water (UPW), pharmaceutical water-for-injection (WFI), clean-in-place (CIP) rinse cycles, environmental effluents, and municipal drinking water distribution systems. The unit delivered is a fully refurbished instrument—originally manufactured between 2020 and 2021—with all critical subsystems (combustion furnace, NDIR detector, catalyst bed, gas purification train, and fluidic manifold) inspected, cleaned, recalibrated, and functionally verified against Shimadzu’s original factory specifications.

Key Features

• High-temperature catalytic oxidation at 680 °C ensures complete mineralization of refractory organics—including humic acids, surfactants, and low-volatility compounds—without acid sparging artifacts.
• NDIR detection provides linear response across 0–30,000 µg/L C with sub-2 µg/L detection limit (as TOC), enabling compliance with stringent regulatory thresholds for WFI (≤ 500 µg/L) and UPW (≤ 100 µg/L).
• Integrated online capability: direct connection to 1/4″ OD tubing, pressure-regulated sample inlet (0.1–0.3 MPa), and programmable cycle timing for scheduled or event-triggered analysis.
• OCT-1 eight-channel autosampler enables sequential analysis of up to eight independent sources—ideal for multi-point monitoring in biopharmaceutical facilities or wastewater treatment plants.
• Robust architecture with ceramic combustion tube, platinum-based catalyst, and dual-stage CO₂ scrubbing (for IC removal) ensures long-term stability and minimal maintenance intervals.
• Comprehensive diagnostics: real-time monitoring of furnace temperature, carrier gas flow, detector signal baseline, and catalyst activity via embedded firmware logs.

Sample Compatibility & Compliance

The TOC-V CSH accepts liquid samples with conductivity ≤ 5 mS/cm and suspended solids 1,000 mg/L), heavy metals (e.g., Fe, Cu > 1 mg/L), or particulates require pre-filtration (0.45 µm) or dilution to prevent catalyst poisoning or optical interference. All measurement protocols align with GLP and GMP documentation requirements: audit trails, user access control, electronic signatures, and data integrity features comply with FDA 21 CFR Part 11 when operated with Shimadzu LabSolutions software (v5.95 or later). Full traceability is maintained through calibrated reference standards (potassium hydrogen phthalate, sodium bicarbonate), system suitability tests (SST), and routine blank verification.

Software & Data Management

Operation and data handling are managed via Shimadzu LabSolutions LC/GC/TOC software (licensed, version 5.95+ included). The interface supports method development, sequence programming, real-time chromatogram visualization, automatic peak integration, and customizable reporting templates (PDF, CSV, XML). Raw data files (.raw) retain full spectral and temporal metadata, including timestamped calibration events, maintenance logs, and error flags. Data export conforms to LIMS-compatible formats and supports automated transfer via FTP or network share. For regulated environments, optional 21 CFR Part 11 modules provide role-based permissions, electronic signature capture, and immutable audit trails covering all analytical actions—from sample injection to report generation.

Applications

• Pharmaceutical manufacturing: Continuous TOC verification of WFI loops, purified water storage tanks, and point-of-use outlets per EU GMP Annex 1 and USP .
• Biotechnology: Monitoring of buffer preparation systems, CIP return lines, and downstream purification skids to detect organic carryover.
• Microelectronics: Ultra-trace TOC control in UPW used for wafer rinsing and photolithography processes.
• Environmental laboratories: Regulatory reporting for EPA Method 415.3 and ISO 8245-compliant wastewater discharge monitoring.
• Power generation: Feedwater and condensate analysis in nuclear and fossil-fuel steam cycles to assess organic fouling potential.

FAQ

Is this instrument supplied with valid calibration certificates?
Yes—each unit ships with a full Shimadzu-certified performance verification report, including TC/IC/TOC linearity, detection limit verification, and system suitability test results using NIST-traceable standards.
Can the TOC-V CSH be integrated into an existing SCADA or DCS environment?
Yes—via Modbus TCP or analog 4–20 mA output (optional module); digital communication requires LabSolutions OPC UA server configuration.
What consumables are required for routine operation?
Catalyst cartridges (every 6–12 months depending on sample load), CO₂ scrubber cartridges (IC removal), quartz combustion tubes (replaced per OEM service schedule), and certified TOC standards.
Does the 6-month warranty cover labor and parts globally?
The warranty covers hardware defects and labor for repair at authorized Shimadzu service centers in North America, Europe, and APAC; international shipping and customs duties are customer-responsible.
Is remote diagnostic support available post-installation?
Yes—Shimadzu-certified engineers provide remote troubleshooting via TeamViewer-assisted screen sharing, subject to prior network authorization and firewall configuration.