Thermo Scientific Heratherm Advanced Drying Oven

Overview

The Thermo Scientific Heratherm Advanced Drying Oven is an engineered solution for precise, repeatable thermal processing in regulated laboratory and industrial quality control environments. Built on a robust stainless-steel or epoxy-coated steel chassis, this series employs either natural convection (OGH models) or mechanically assisted forced convection (OMH models) to deliver tightly controlled heating, drying, sterilization, and aging applications. Its operational temperature range spans from +50 °C to 330 °C—enabling both low-temperature moisture removal and high-temperature material conditioning. The oven’s core architecture prioritizes thermal fidelity: advanced PID-based controllers with real-time temperature compensation, dual-sensor monitoring (chamber and ambient), and optimized airflow management ensure stability within ±0.2 °C and uniformity as tight as ±1.3 °C at 150 °C across the full working volume. Designed for long-term reliability under continuous operation, the Heratherm Advanced series meets the physical and procedural demands of pharmaceutical stability testing, polymer curing, residual solvent analysis, and ISO/IEC 17025-accredited calibration workflows.

Key Features

• Programmable controller supporting up to 10 multi-step protocols (each with ramp/soak segments), enabling unattended operation for extended thermal cycles.
• Electronically regulated fan speed and adjustable air inlet/outlet positioning—allowing application-specific airflow optimization from gentle drying to rapid heat recovery.
• BOOST function for accelerated temperature ramping without overshoot, reducing cycle time while preserving sample integrity.
• Energy-efficient thermal design: verified power consumption as low as 170 W/h (natural convection, 60 L chamber at 150 °C) and 259 W/h (forced convection, same conditions).
• Optional stainless-steel interior and exterior finish (SS variants) compliant with USP and EU GMP Annex 1 requirements for cleanroom-compatible equipment.
• Dual-access sensor ports for integration with external calibrated thermistors or data loggers—supporting independent validation and audit-ready traceability.
• Intuitive touchscreen interface with password-protected user levels, configurable alarm thresholds, and automatic error logging.

Sample Compatibility & Compliance

The Heratherm Advanced series accommodates diverse sample formats—including glassware, metal trays, polymer molds, and sealed containers—across chamber volumes from 61 L to 170 L. Internal dimensions support standard ISO stacking configurations and allow flexible shelving (2–19 positions, 25 kg max load per shelf). All models are CE-marked and constructed to meet IEC 61010-1 safety standards for laboratory electrical equipment. When paired with validated external sensors and compliant software, the system supports regulatory documentation requirements under FDA 21 CFR Part 11 (electronic records/signatures), ISO 17025 (testing and calibration laboratories), and EU GMP Annex 15 (qualification and validation). Routine calibration is simplified via built-in offset adjustment routines traceable to NIST-certified references.

Software & Data Management

While the onboard controller provides standalone protocol execution and local event logging, the Heratherm Advanced integrates seamlessly with Thermo Fisher’s optional ChronoLog™ Data Acquisition System. This platform enables real-time remote monitoring, automated CSV export, and time-stamped audit trails with user-defined metadata fields (operator ID, batch number, SOP reference). All logged data include timestamps synchronized to UTC, digital signatures, and immutable storage—fulfilling ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available). For facilities operating under GxP frameworks, optional IQ/OQ/PQ documentation packages are available to accelerate installation and operational qualification.

Applications

• Pharmaceutical stability studies per ICH Q1 guidelines (long-term, accelerated, intermediate conditions).
• Moisture content determination (ASTM D2240, ISO 11358) and gravimetric residue analysis.
• Curing of adhesives, coatings, and composite pre-pregs under controlled thermal profiles.
• Pre-conditioning of test specimens prior to mechanical or rheological evaluation (e.g., ASTM D638, ISO 527).
• Depyrogenation of glassware and stainless-steel components in sterile manufacturing environments.
• Accelerated aging of packaging materials (ISO 11607) and medical device components.

FAQ

What convection options are available, and how do they affect thermal performance?
The Heratherm Advanced offers two distinct airflow architectures: natural convection (OGH series) for minimal sample disturbance and forced convection (OMH series) for enhanced uniformity and faster equilibration. OMH models achieve tighter temperature uniformity (±1.3 °C at 150 °C) and improved stability (±0.2 °C) due to precisely regulated fan-assisted circulation.
Can the oven be validated for GMP use?
Yes—when equipped with external calibrated sensors and used with ChronoLog™ software, the system supports full IQ/OQ/PQ execution and complies with FDA 21 CFR Part 11, EU Annex 11, and ISO/IEC 17025 documentation requirements.
Is stainless-steel construction available for all chamber sizes?
Stainless-steel exterior and interior variants (SS suffix) are offered across all six base models (OGH60 SS through OMH180 SS), ensuring compatibility with stringent cleaning and corrosion resistance protocols.
How is temperature accuracy maintained over time?
The controller includes an internal self-diagnostics routine and supports user-executed offset calibration using a traceable reference thermometer—ensuring ongoing accuracy without requiring factory service.
What power supply configurations are supported?
All models operate on 230 V AC, 50 Hz single-phase input. No 60 Hz or 115 V variants are available in the Advanced series; dedicated voltage transformers are required for non-standard grids.