Thermo Scientific Indiko Series Fully Automated Clinical Chemistry Analyzer
| Brand | Thermo Scientific |
|---|---|
| Origin | Global Manufacturing Network |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Model | Indiko / Indiko Plus |
| Pricing | Available Upon Request |
Overview
The Thermo Scientific Indiko Series Fully Automated Clinical Chemistry Analyzer is a compact, benchtop clinical chemistry system engineered for precision, reliability, and operational efficiency in low- to mid-volume diagnostic laboratories. Based on photometric measurement principles—specifically absorbance detection across a broad spectral range (340–800 nm) using solid-state light sources—the Indiko platform delivers quantitative analysis of enzymatic, colorimetric, and immunoturbidimetric assays. Designed for both human clinical diagnostics and veterinary applications, the system supports standardized methodologies compliant with CLSI EP15-A3 and ISO 15197:2013 frameworks. Its modular architecture integrates sample aspiration, reagent dispensing, reaction incubation, photometric reading, and waste management within a single footprint—eliminating dependency on external water purification or drainage infrastructure.
Key Features
- Compact benchtop design (W × D × H: 65 × 60 × 45 cm), optimized for space-constrained environments including point-of-care clinics, reference labs, and veterinary hospitals.
- Minimal sample requirement of 2 µL—enabling comprehensive biochemical profiling from capillary blood draws in small-animal models (e.g., mice, rabbits, cats, dogs, and equine neonates).
- Automated clot detection via real-time optical scanning prior to aspiration, preventing clogging and ensuring assay integrity.
- Integrated sample pre-dilution and post-analytical retesting logic—triggered automatically based on flagging rules (e.g., out-of-linear-range results or abnormal blank absorbance).
- Reagent and sample capacity flexibility: accommodates up to 40 samples per run (in primary tubes, microtubes, or sample racks) and 24 reagent positions with onboard refrigeration (4–12 °C).
- Long-life LED-based optical source with no scheduled lamp replacement—reducing downtime and lifecycle maintenance costs.
- Continuous loading capability: samples, reagents, and disposable cuvettes can be added during operation without interrupting ongoing assays.
Sample Compatibility & Compliance
The Indiko Series accepts a wide range of biological matrices—including serum, plasma (EDTA/Li-heparin), whole blood (with centrifugation step), urine, cerebrospinal fluid (CSF), and saliva—without hardware modification. Sample tube compatibility includes standard 13 × 75 mm, 13 × 100 mm, and microtubes (0.5 mL). All assays are validated against CLIA-waived and CE-IVD marked test menus, with traceability to NIST SRMs where applicable. The system supports LIS connectivity via ASTM E1384 and HL7 v2.5.1 protocols and meets IEC 61010-1 safety requirements and EN 61326-1 EMC standards. For regulated environments, audit trails, user access controls, and electronic signature support align with FDA 21 CFR Part 11 and EU Annex 11 expectations when deployed with Thermo Fisher’s optional LIMS-integrated software suite.
Software & Data Management
Indiko instruments operate under the Thermo Scientific Indiko Software Suite—a Windows-based application offering method configuration, QC charting (Levey-Jennings, Westgard rules), calibration curve management, and automated result flagging. Raw absorbance data, reaction kinetics curves, and error logs are stored in encrypted SQLite databases with configurable retention policies. Export formats include CSV, PDF reports, and HL7 ORU messages. The software supports multi-level user roles (Operator, Supervisor, Administrator) with password complexity enforcement and session timeout. All critical actions—including calibration, QC run, result override, and method edit—are timestamped and attributed with operator ID, satisfying GLP/GMP documentation requirements.
Applications
- Clinical chemistry profiling in outpatient clinics and community hospitals: liver function (ALT, AST, ALP, GGT), renal markers (creatinine, urea), lipid panels (cholesterol, triglycerides), electrolytes (Na⁺, K⁺, Cl⁻), and cardiac biomarkers (CK-MB, LDH).
- Veterinary diagnostics: species-specific reference interval interpretation for canine, feline, equine, and bovine panels; integration with IDEXX and Antech-compatible test codes.
- Research applications requiring high reproducibility at low sample volumes—e.g., longitudinal metabolic studies in rodent models or pharmacokinetic monitoring in preclinical trials.
- Emergency department triage: rapid turnaround (<15 min for 12-test panel) enabled by parallel processing and minimal hands-on time.
FAQ
What sample types are supported by the Indiko analyzer?
Serum, plasma (EDTA or lithium heparin), whole blood (post-centrifugation), urine, CSF, and saliva—all processed without dilution unless analyte concentration exceeds linear range.
Does the Indiko require connection to a central water supply or drain?
No. It operates with internal waste reservoirs and uses air-drying technology for cuvette cleaning—no external plumbing required.
Is the system compatible with laboratory information systems (LIS)?
Yes. ASTM E1384 and HL7 v2.5.1 interfaces are standard; bi-directional communication supports auto-verification and result routing.
Can the Indiko perform reflex testing or rule-based reanalysis?
Yes. Configurable reflex rules trigger automatic reruns, dilutions, or alternate methods based on initial result flags or QC failures.
What regulatory certifications does the Indiko hold?
CE-IVD marking (Class B), FDA 510(k) clearance (K201239), and compliance with ISO 13485:2016 quality management system requirements.
