WIGGENS Vdose PRO Peristaltic Pump

Overview

The WIGGENS Vdose PRO Peristaltic Pump is an engineered solution for precise, contamination-free fluid handling in regulated laboratory environments. Operating on the principle of peristalsis—where rollers compress flexible tubing to generate positive displacement—the Vdose PRO eliminates fluid contact with internal pump components, ensuring zero dead volume and preventing cross-contamination. This makes it especially suitable for shear-sensitive biologics, viscous pharmaceutical syrups, corrosive reagents, and sterile media transfer applications. Designed and assembled to German engineering standards, the pump integrates a high-resolution stepper motor drive system capable of delivering reproducible volumetric delivery across its full operational range. Its compact low-profile chassis (330 mm height) allows seamless integration into biosafety cabinets, fume hoods, and automated liquid handling workstations without compromising ergonomic access or spatial efficiency.

Key Features

• Bidirectional operation (clockwise and counter-clockwise) enables both dispensing and aspiration—critical for recirculation, backflushing, or reversible process control.
• Four standard tube diameter options (2 mm, 3 mm, 6 mm, and 8 mm) with dual wall thickness support (1.6 mm and 2.3 mm), allowing optimization for flow rate, pressure resistance, and chemical compatibility.
• 4-inch chemically resistant LCD display with intuitive icon-based navigation and multi-language interface (English, German, French, Spanish, Chinese) for global lab usability.
• Programmable memory for up to nine user-defined protocols—including dispense volume, speed ramp profiles, pause intervals, and direction sequences—enabling repeatable method execution without manual intervention.
• Five-stage acceleration ramp control minimizes pulsation and ensures smooth start-up, reducing mechanical stress on tubing and improving long-term hose life and flow stability.
• Remote control capability via analog voltage input (0–10 V) or digital TTL signal supports integration into PLC-controlled systems, LIMS workflows, or custom automation platforms.
• Modular pump head architecture permits future expansion: single-head configuration is standard, but dual-head or multi-channel configurations can be added without replacing the base unit.

Sample Compatibility & Compliance

The Vdose PRO is validated for use with a broad spectrum of challenging fluids, including glycerol-based formulations, cell culture media, acidic or alkaline buffers, organic solvents (with compatible tubing), and particulate-laden suspensions. Its non-invasive fluid path preserves sample integrity—particularly vital for shear-thinning polymers, protein solutions, and microbial cultures where laminar flow and minimal turbulence are required. All electrical and mechanical designs comply with international safety and environmental directives: UL 61010-1, CSA C22.2 No. 61010-1, EN 61326-1 (EMC), EN 61000-6-2/6-4, CE marking, RoHS 2011/65/EU, and WEEE 2012/19/EU. While not inherently 21 CFR Part 11 compliant, audit trails and electronic record integrity can be achieved when paired with validated third-party software platforms supporting ALCOA+ principles.

Software & Data Management

The Vdose PRO operates as a standalone instrument with embedded firmware; no proprietary PC software is required for basic operation. However, its analog/digital I/O interface supports integration with laboratory data acquisition systems (e.g., LabVIEW, MATLAB, or SCADA platforms) for real-time flow monitoring, event logging, and synchronized triggering. Time-stamped protocol execution records—including speed, volume delivered, direction, and error codes—are stored internally and retrievable via front-panel review. For GxP environments, external validation documentation (IQ/OQ/PQ templates) is available upon request and aligns with ISO/IEC 17025 and ASTM E2500 guidance for equipment qualification.

Applications

• Microbiology: Sterile inoculum transfer, continuous feeding in bioreactors, and gradient dilution series preparation for MIC/MBC assays.
• Pharmaceutical Development: Accurate metering of excipients during oral liquid formulation, buffer exchange in purification workflows, and fill-volume verification in vial filling simulations.
• Food & Beverage R&D: Viscosity-adapted dosing of syrups, emulsions, and functional ingredients under controlled shear conditions.
• Chemical Process Optimization: Reagent addition in flow chemistry reactors, catalyst slurry pumping, and corrosion-resistant acid/base delivery in electrochemical cells.
• Environmental Testing: Automated sampling from aqueous streams, leachate analysis, and sequential extraction protocols requiring precise timing and volume fidelity.

FAQ

What tubing materials are recommended for use with the Vdose PRO?
Standard recommendations include platinum-cured silicone (for general-purpose use), Viton® (for solvent resistance), and Tygon® B-44-3 (for UV transparency and low extractables). Tubing selection must consider chemical compatibility, pressure rating, and regulatory requirements (e.g., USP Class VI for pharmaceutical applications).
Can the Vdose PRO be calibrated to meet GLP standards?
Yes—calibration is traceable to NIST-certified volumetric standards using gravimetric or timed-collected volume methods. Calibration certificates, uncertainty budgets, and SOP templates are provided with optional qualification packages.
Is the pump suitable for continuous operation over extended periods?
The Vdose PRO is rated for continuous duty at speeds ≤300 rpm with appropriate tubing cooling and maintenance intervals. Thermal management is enhanced by passive convection design and low-power stepper motor architecture.
How does bidirectional operation improve experimental flexibility?
Reversible flow enables closed-loop circulation, automatic priming, residual volume recovery, and dynamic flow reversal for cleaning-in-place (CIP) routines—reducing manual handling and increasing process robustness.
What is the minimum programmable dispense volume?
With optimized tubing and speed settings, reproducible dispensing down to 0.1 mL is achievable. Actual resolution depends on tube inner diameter, rotational precision, and dwell time accuracy—validated per ASTM D3418 for volumetric repeatability.