Chemyx Fusion 200-X Dual-Channel Modular Syringe Pump

Overview

The Chemyx Fusion 200-X is a high-precision, dual-channel modular syringe pump engineered for reproducible, pulseless fluid delivery in demanding laboratory environments. It operates on a stepper motor–driven linear actuation principle, translating rotational motion into highly controlled axial displacement of syringe plungers with sub-microliter resolution. This architecture eliminates mechanical backlash and ensures consistent volumetric displacement across the full operational range — from nanoliter-per-minute infusions required in microdialysis or single-cell electrophysiology to milliliter-per-minute reagent dosing in continuous-flow reactors. Designed for integration into automated workflows, the Fusion 200-X supports both forward injection and reverse withdrawal modes, enabling bidirectional fluid handling essential for closed-loop perfusion systems, solvent exchange protocols, and gradient elution setups.

Key Features

• Dual independent channels with synchronized or asynchronous operation — each channel fully programmable with separate flow profiles, dwell times, and direction control.
• Modular expansion capability: up to 11 syringe pump modules can be daisy-chained via RS-232, allowing scalable multi-channel configurations without external controllers.
• High-resolution 4.3-inch color LCD touchscreen interface with intuitive icon-based navigation, real-time flow visualization, and on-device parameter logging.
• Ultra-wide dynamic flow range spanning six orders of magnitude: 0.0001 µL/min (ideal for nanofluidic assays) to 85 mL/min (suitable for high-throughput reagent dispensing).
• Robust mechanical design delivering 65 lbf (29.4 kgf) linear force — compatible with glass, polypropylene, and stainless-steel syringes ranging from 0.5 µL microsyringes to 60 mL reservoirs.
• Built-in TTL trigger I/O for hardware synchronization with external instruments including mass spectrometers, fluorescence detectors, and electrophysiology amplifiers.

Sample Compatibility & Compliance

The Fusion 200-X accommodates standard Luer-lock and Luer-slip syringes manufactured from borosilicate glass, polypropylene, or PTFE-coated materials — ensuring chemical compatibility with organic solvents, aqueous buffers, viscous polymer solutions, and biological media. Its flow path contains no wetted elastomers or diaphragms, eliminating leachables and reducing contamination risk in sensitive applications such as stem cell delivery or neuropharmacological infusion. The system complies with general-purpose laboratory equipment safety standards (IEC 61010-1) and supports audit-ready operation when integrated with validated software platforms adhering to FDA 21 CFR Part 11 requirements for electronic records and signatures. While not certified for GMP manufacturing use out-of-the-box, its deterministic flow behavior and traceable calibration history make it suitable for GLP-compliant preclinical research and method development under controlled SOPs.

Software & Data Management

Chemyx provides FusionTouch™ PC software (Windows-compatible) for advanced protocol scripting, multi-step ramped flow profiles, real-time data streaming, and CSV export of time-stamped flow logs. The software supports direct command-line control via ASCII-based RS-232 protocol, enabling seamless integration into LabVIEW, Python (PySerial), MATLAB, or custom C# automation frameworks. All user-defined methods are stored with metadata including timestamp, operator ID, syringe type, and calibration offset — facilitating traceability in regulated environments. Firmware updates are delivered through signed binary packages with version-controlled release notes, and device-level configuration backups can be exported for system recovery or cross-lab replication.

Applications

• Mass spectrometry sample introduction: stable nanoflow LC-MS coupling and chip-based electrospray infusion.
• Microfluidic device priming and long-term perfusion: maintaining laminar flow in organ-on-chip platforms and microreactors.
• In vivo neuroscience studies: stereotaxic delivery of neurotransmitters, viral vectors, or optogenetic agents into rodent brain tissue with picoliter precision.
• Electrospinning process control: metered polymer solution feed for fiber diameter consistency and morphology reproducibility.
• Automated reaction screening: sequential reagent addition in parallel synthesis reactors with programmable delay intervals and concentration gradients.
• Cell culture media exchange: gentle, non-shear replacement in 3D spheroid or organoid cultures over extended durations.

FAQ

Can the Fusion 200-X operate in closed-loop feedback mode using external sensor input?
No — the pump does not natively support analog feedback control; however, third-party PID controllers or PLCs can interface via TTL triggers and RS-232 commands to implement adaptive flow regulation.
Is calibration traceable to NIST standards?
Chemyx provides factory calibration certificates with uncertainty budgets referenced to ISO/IEC 17025-accredited metrology labs; end-users may perform in-house verification using gravimetric or fluorometric flow validation methods.
What syringe sizes are supported without adapter kits?
All standard syringes from 0.5 µL microsyringes (e.g., Hamilton 7000 series) up to 60 mL glass or plastic syringes mount directly using the included universal syringe holders.
Does the system support continuous unattended operation for >72 hours?
Yes — thermal management and low-power stepper drivers enable stable 24/7 operation; users must ensure appropriate syringe integrity, fluid degassing, and tubing selection to prevent occlusion or bubble formation.
How is firmware updated, and is rollback supported?
Firmware updates are performed via USB-connected Windows PC using Chemyx’s signed updater utility; previous versions are archived automatically, and manual rollback is supported through firmware image restoration.