METTLER TOLEDO Pipet-Lite XLS+ Single-Channel Manual Pipette
| Brand | METTLER TOLEDO |
|---|---|
| Origin | USA |
| Model | L-10XLS+/L-20XLS+/L-100XLS+ |
| Channel Count | 1 |
| Maximum Volume | 2000 µL |
| Accuracy | ±1% at 20 µL, ±0.8% at 200 µL |
| Automation Level | Manual |
| Sterilization | Fully Autoclavable (Liquid End, Sleeve, Ejector) |
| RFID Integration | Yes (for Calibration Tracking & Inventory Management) |
| Tip Ejection System | LTS™ LightTouch System with High-Density Polymer Ejector |
Overview
The METTLER TOLEDO Pipet-Lite XLS+ Single-Channel Manual Pipette is an engineered precision liquid handling instrument designed for high-reproducibility volumetric transfer in regulated laboratory environments. Built upon the proven Couette-flow–informed piston displacement principle, it delivers traceable, ISO/IEC 17025–aligned performance across its full operational range—from 0.1 µL to 20 mL—depending on model variant. Unlike conventional air-displacement pipettes subject to environmental drift, the XLS+ platform incorporates a thermally stable, low-hysteresis stainless-steel piston assembly and hermetically sealed O-ring architecture that minimizes evaporation-induced volume deviation and operator-induced variability. Its mechanical design conforms to ergonomic standards defined in ISO 9241-5 and ASTM F1623, reducing biomechanical load during extended use—critical for GLP-compliant assay workflows and high-throughput QC laboratories where operator fatigue directly impacts data integrity.
Key Features
- Patented Magnetic Assist™ technology reduces plunger activation force by up to 45% compared to standard manual pipettes, enabling consistent aspiration and dispensing with minimal thumb exertion.
- LTS™ (LightTouch System) tip attachment and ejection mechanism ensures uniform, low-force tip seating and one-step, tactile-positive ejection—even with gloves on—eliminating tip wobble and seal inconsistency.
- Autoclavable liquid end, sleeve, and high-density polymer ejector withstand repeated cycles at 121°C, 1 bar saturated steam for ≥20 minutes without dimensional or functional degradation.
- Integrated RFID tag (ISO 15693 compliant) stores unique serial number, calibration history, service logs, and user-defined metadata—enabling seamless integration with LIMS and electronic lab notebooks (ELN).
- Ergonomic soft-grip handle with contoured geometry and balanced mass distribution (center of gravity optimized at 32 mm from grip axis) reduces wrist extension torque during repetitive operations.
- Tool-free volume adjustment dial features tactile detents and anti-slip knurling; calibrated scale remains legible after >50,000 rotational cycles.
Sample Compatibility & Compliance
The Pipet-Lite XLS+ is validated for aqueous, viscous (up to 500 cP), and volatile solvents—including ethanol, DMSO, and 70% glycerol—without requiring recalibration. All wetted materials comply with USP Class VI biocompatibility requirements and are free of phthalates, latex, and heavy metals. Device firmware and RFID data structures support 21 CFR Part 11–compliant audit trails when paired with METTLER TOLEDO’s LabX® Pipette Software. Full documentation packages—including Factory Calibration Certificates (traceable to NIST SRM 2192), IQ/OQ protocols, and risk assessments—are available per request for GMP-regulated facilities.
Software & Data Management
When connected via optional USB reader or Bluetooth-enabled docking station, the XLS+ synchronizes calibration events, usage counters, and maintenance alerts directly into LabX Pipette Software. This enables automated generation of calibration certificates (per ISO 8655-6), overdue service notifications, and fleet-wide compliance dashboards. Audit trail records capture timestamped operator ID, action type (e.g., “volume adjusted”, “RFID read”), and system hash—fully compliant with ALCOA+ principles. Data export supports CSV, PDF, and XML formats for integration with enterprise quality management systems (QMS).
Applications
The XLS+ is routinely deployed in pharmaceutical QC labs for dissolution testing, potency assays, and reference standard preparation; in clinical diagnostics for ELISA plate setup and nucleic acid dilution; and in academic research for single-cell RNA-seq library construction where sub-microliter accuracy and tip-to-tip consistency are non-negotiable. Its LTS compatibility ensures reliable performance with third-party low-retention tips certified to ISO 8655-8, while autoclavability supports sterile cell culture applications without cross-contamination risk.
FAQ
Is the entire pipette autoclavable?
Yes—the liquid end, sleeve, and ejector are fully autoclavable as a unit at 121°C, 1 bar for 20 minutes. The upper body housing is not autoclavable but may be surface-sanitized with 70% ethanol.
Does the RFID chip require a battery or external power?
No—it is passive RFID (13.56 MHz, ISO 15693), powered wirelessly during interrogation by the reader.
Can I use non-LTS tips with this pipette?
Standard conical tips may be used, but LTS tip compatibility is required to guarantee specified accuracy, repeatability, and ergonomic performance.
What calibration standards does METTLER TOLEDO follow?
All factory calibrations adhere to ISO 8655-6 and are traceable to NIST Standard Reference Material 2192 (gravimetric water delivery standard).
How often should I recalibrate the pipette?
Frequency depends on usage intensity and regulatory requirements—typically every 3–6 months for GLP labs, or after 10,000 pipetting cycles, whichever occurs first.
