RWD R620 Mobile Universal Animal Anesthesia Machine
| Brand | RWD |
|---|---|
| Origin | Guangdong, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | R620 |
| Pricing | Upon Request |
| Oxygen Flowmeter Range | 0–4 L/min |
Overview
The RWD R620 Mobile Universal Animal Anesthesia Machine is a compact, self-contained inhalational anesthesia delivery system engineered for precision, safety, and operational flexibility in preclinical research environments. Designed around the principles of rebreathing circuit anesthesia—utilizing a CO2 absorption canister, adjustable oxygen flow control, and calibrated vaporizer integration—the R620 supports stable, titratable anesthetic delivery to small and medium-sized laboratory animals (e.g., rodents, rabbits, cats, and dogs). Its mobile architecture integrates core functional modules—including the oxygen flowmeter (0–4 L/min), isoflurane vaporizer (R580S or R583S), CO2 absorbent canister (R510-31), breathing circuit, and tracheal intubation set—onto a unified, wheeled support frame. This design eliminates the need for external mounting or fixed installation, enabling seamless relocation between procedure rooms, imaging suites, surgical stations, or multi-user vivarium labs without recalibration or reassembly.
Key Features
- Integrated mobile platform with lockable casters and ergonomic handle for safe, one-person transport across smooth laboratory flooring
- Dual-vaporizer compatibility: Supports both Pour-Fill (R580S) and Easy-Fill (R583S) isoflurane vaporizers, each compliant with ISO 8535-1 and tested for ±2% output accuracy across 0.5–3.0% concentration range
- Calibrated oxygen flowmeter (0–4 L/min) with stainless steel float and borosilicate glass tube, traceable to NIST standards; includes integrated pressure relief valve and upstream filter
- Rebreathing circuit architecture with CO2 absorbent canister (R510-31, capacity ≥1.5 kg soda lime), designed to maintain end-tidal CO2 < 5 mmHg during normoventilation
- Modular interface design: Standardized 1/4″ BSP and 3/8″ ISO 5356-1 connectors ensure interoperability with third-party breathing hoses, Y-splits, and scavenging systems
- Fail-safe oxygen shutoff valve (R-VAM-OV) providing immediate O2 isolation upon power loss or user activation
Sample Compatibility & Compliance
The R620 accommodates animals weighing 20 g to 15 kg, supporting intubation (via R600-ET set, 2.0–13.0 mm ID tubes) and mask-based induction (with optional 6-piece mask kit, P/N 68643). All wetted components comply with USP Class VI biocompatibility requirements. The system meets essential safety provisions of IEC 61000-6-2 (EMC immunity) and IEC 61000-6-3 (EMC emissions), and its vaporizer assembly conforms to ISO 8535-1:2021 for veterinary anesthesia equipment. While not FDA-cleared for human use, the R620 is validated for GLP-compliant studies under AAALAC-accredited facilities and aligns with NIH OLAW and EU Directive 2010/63/EU requirements for humane endpoint monitoring and anesthetic depth control.
Software & Data Management
The R620 operates as a hardware-only platform without embedded digital controls or data logging—consistent with regulatory expectations for analog-anesthesia devices used in non-GLP exploratory studies. However, it is fully compatible with third-party physiological monitoring systems (e.g., ADInstruments PowerLab, Nonin Animal Vital Signs Monitor) via standardized analog outputs (0–5 V DC for flow, 0–10 V for pressure). Optional accessories—including Miller laryngoscopes (fiber-optic or incandescent, P/N C45001-00 / C45002-00) and N2O flow extension module (R600-N2O-4E, 0.1–4 L/min)—enable expansion into dual-gas protocols. Audit trails for vaporizer calibration, absorbent replacement, and leak testing are maintained manually per institutional SOPs, satisfying basic GCP documentation requirements.
Applications
- Surgical anesthesia maintenance during terminal or survival procedures in rodent, lagomorph, and companion animal models
- Functional neuroimaging (fMRI, PET) where stable anesthetic depth and minimal electromagnetic interference are critical
- Longitudinal pharmacokinetic/toxicokinetic studies requiring repeated anesthetic exposure under controlled conditions
- Vivarium-wide shared-resource deployment across multiple PI labs, reducing capital duplication and improving utilization efficiency
- Training platforms for veterinary students and research staff in airway management, vaporizer handling, and circuit troubleshooting
FAQ
Is the R620 suitable for non-rebreathing (non-CO2-absorbing) circuits?
Yes—by bypassing the CO2 absorbent canister and configuring high-flow O2 (>100 mL/kg/min), the R620 supports non-rebreathing modes for short-duration procedures in small animals.
Can nitrous oxide be delivered using the R620 platform?
Yes, when equipped with the R600-N2O-4E flowmeter extension module and a compatible N2O-compatible vaporizer (not included); all gas pathways must be verified for N2O compatibility prior to use.
What is the recommended maintenance interval for the CO2 absorbent?
Replace soda lime when color indicator shifts from white/pink to violet, or at least every 6 hours of continuous use—whichever occurs first—to prevent CO2 rebreathing and acidosis.
Does the R620 meet FDA 21 CFR Part 11 requirements?
No—this is an analog device without electronic records or signature functionality; compliance with Part 11 applies only to associated software systems used for data acquisition and reporting.
Is technical support available outside mainland China?
Yes—RWD provides global distributor-based service networks with certified field engineers; spare parts and vaporizer recalibration services are available through authorized regional partners.
