IKA LR 1000 basic Package Laboratory Reactor System
| Brand | IKA |
|---|---|
| Origin | Germany |
| Model | LR 1000 basic Package |
| Usable Volume | 1000 mL (max), 500 mL (min without disperser), 300 mL (min with disperser) |
| Operating Temperature Range | Up to 120 °C (heating up to 180 °C), Cooling Medium Inlet ≥3 °C |
| Working Pressure | Low-pressure operation, vacuum capability down to 25 mbar |
| Speed Range | 10–150 rpm (adjustable in 1 rpm increments) |
| Torque | 3 Nm |
| Heating Power | 1000 W |
| Total Input Power | 1200 W |
| Temperature Control Accuracy | ±1 K (with integrated sensor), ±0.2 K (with external PT100) |
| Speed Deviation | ±5 rpm |
| Temperature Measurement Resolution | 0.1 K |
| Material of Wetted Parts | AISI 316L stainless steel, Borosilicate Glass 3.3, PTFE, PEEK, FKM |
| Sealing Interfaces | 1 × NS 29/32, 3 × NS 14/23 |
| Safety Features | Adjustable upper/lower temperature limits (225 °C / 47 °C), deviation thresholds (±20 K / ±10 K), automatic shutdown on lid opening or vessel removal, manual safety circuit, thermal cut-off fuse |
| Connectivity | RS232, USB, analog output not available |
| Protection Rating | IP21 (DIN EN 60529) |
| Dimensions (W×D×H) | 443 × 360 × 295 mm |
| Weight | 16 kg |
| Ambient Conditions | 5–40 °C, ≤80% RH |
| Compliance | CE-marked, conforms to IEC 61010-1 for laboratory equipment safety |
Overview
The IKA LR 1000 basic Package is a modular, benchtop laboratory reactor system engineered for precise thermal and mechanical control during chemical synthesis, formulation development, and process optimization. It operates on the principle of jacketed or bottom-heated temperature regulation—where thermal energy is transferred via conduction from an integrated heating plate beneath the borosilicate glass reaction vessel—enabling stable, reproducible temperature profiles across a wide operational range. Designed for low-pressure applications—including atmospheric, inert-gas-purged, and moderate vacuum conditions (down to 25 mbar)—the system supports scalable reaction workflows in pharmaceutical, cosmetic, and fine chemical R&D laboratories. Its architecture integrates mechanical agitation, real-time temperature monitoring, and programmable safety logic into a single compact unit, eliminating the need for external controllers in standard use cases.
Key Features
- Modular design with standardized NS 29/32 and NS 14/23 ground-glass interfaces for seamless integration with condensers, dropping funnels, gas inlets, pH electrodes, or reflux assemblies.
- Dual-mode temperature control: built-in heating plate (max 180 °C) coupled with optional external cooling loop connection (via rear-panel inlet/outlet ports) for active temperature modulation between 3 °C and 120 °C.
- Precision speed regulation from 10 to 150 rpm in 1-rpm increments, driven by a high-torque (3 Nm), brushless DC motor with LED-displayed feedback and ±5 rpm repeatability.
- Comprehensive safety architecture including lid-open and vessel-removal interlocks, adjustable upper/lower thermal limits (configurable via front panel), and automatic thermal cut-off fuse compliant with IEC 61010-1.
- Integrated PT100.5 temperature sensor (included) with dedicated mounting fixture (LR 1000.61), delivering ±0.2 K accuracy when used with external reference calibration.
- Digital user interface with seven-segment LED displays for simultaneous monitoring of speed, setpoint temperature, actual temperature, timer, and safety status indicators.
- RS232 and USB ports support bidirectional data logging and remote parameter adjustment using IKA Labworldsoft™ or third-party SCADA-compatible software.
Sample Compatibility & Compliance
The LR 1000 basic Package accommodates reaction volumes from 300 mL (when using ULTRA-TURRAX® T 25 disperser tools) to 1000 mL (standard configuration), making it suitable for small-batch synthesis, emulsion development, crystallization studies, and polymerization screening. All fluid-contact materials—including vessel body (Duran® borosilicate glass 3.3), stirring shaft seals (FKM), scraper blades (PTFE-coated, optional), and gasketing (PEEK/PTFE)—are chemically resistant to common organic solvents, aqueous buffers, and mild acids/bases. The system complies with EU Directive 2014/30/EU (EMC), 2014/35/EU (LVD), and carries CE marking per IEC 61010-1:2010 for safety in laboratory environments. While not inherently 21 CFR Part 11–compliant, audit-trail-capable data export via Labworldsoft enables alignment with GLP/GMP documentation requirements when deployed within validated workflows.
Software & Data Management
Data acquisition and system control are supported through IKA’s Labworldsoft™ software (v5.0+), which provides time-stamped logging of speed, temperature, torque, and timer values at user-defined intervals. Raw data exports as CSV or Excel-compatible files for downstream statistical analysis (e.g., DoE, kinetic modeling). USB and RS232 interfaces allow direct connection to Windows-based PCs; no proprietary drivers are required. The system stores up to 10 user-defined protocols internally, each containing ramp/soak temperature profiles, speed sequences, and timer settings. All parameter changes are reflected in real time on the front-panel display, and firmware updates are delivered via USB stick—ensuring long-term maintainability without hardware modification.
Applications
- Pharmaceutical preformulation: solvent-mediated polymorph screening, API crystallization under controlled supersaturation and agitation.
- Cosmetic emulsion development: phase inversion studies, viscosity profiling during homogenization, and stability testing under thermal cycling.
- Organometallic catalysis: air-sensitive reactions under nitrogen/argon blanket, with inline temperature feedback during exothermic addition steps.
- Polymer synthesis: step-growth condensation reactions requiring precise stoichiometric mixing and gradual temperature ramping.
- Green chemistry process evaluation: solvent-free mechanochemical reactions enabled by high-torque anchoring impellers (optional PTFE刮片).
- Quality-by-Design (QbD) experimentation: multivariate DoE campaigns leveraging programmable temperature-speed-timing combinations.
FAQ
What is the minimum recommended working volume when using the ULTRA-TURRAX® T 25 disperser?
The system supports dispersion operations starting from 300 mL, provided the T 25 tool is fully immersed and vortex formation is minimized via appropriate baffle placement.
Can the LR 1000 basic Package operate under full vacuum?
It is rated for vacuum down to 25 mbar; continuous operation below this threshold requires additional pressure-rated vessel accessories and is not covered under standard warranty.
Is the heating plate capable of reaching 180 °C during normal operation?
Yes—the 180 °C maximum is intended for dry-heating mode (e.g., vessel pre-drying); process temperature limits remain capped at 120 °C unless explicitly validated for higher thermal loads.
Does the system support GLP-compliant electronic records?
While the hardware lacks embedded audit trail functionality, Labworldsoft™ enables secure, timestamped data export with operator ID tagging—sufficient for GLP-aligned documentation when paired with institutional SOPs.
What cooling media are compatible with the rear-panel cooling ports?
Chilled water or glycol-water mixtures (≤30 % concentration) at inlet temperatures ≥3 °C and flow rates ≥0.5 L/min are recommended; refrigerated circulators must be externally regulated to avoid condensation-induced electrical hazards.
