METTLER TOLEDO Rainin SmartCheck Pipette Verification System
| Brand | METTLER TOLEDO |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Status | Authorized Distributor |
| Product Origin | Domestic |
| Model No. | 30564095 |
| Instrument Type | Single-Channel Pipette |
| Automation Level | Motorized |
| Channel Count | Single |
| Volume Range | 10–1000 µL |
| Maximum Capacity | 10 mL |
| Accuracy Tolerance | ±3–10% |
Overview
The METTLER TOLEDO Rainin SmartCheck Pipette Verification System is a compact, benchtop gravimetric verification instrument engineered for rapid, traceable performance assessment of single-channel and multi-channel pipettes. It operates on the principle of high-precision mass measurement—converting dispensed liquid volume (typically deionized water at controlled ambient conditions) into mass via an integrated analytical balance, then applying ISO 8655-compliant density and buoyancy corrections to derive true volumetric delivery. Designed for laboratories operating under GLP, GMP, or ISO/IEC 17025 frameworks, SmartCheck delivers objective, audit-ready pass/fail determinations in under 60 seconds per test sequence—without requiring calibration standards, reference liquids beyond DI water, or external software during basic operation.
Key Features
- Rapid verification cycle: Full gravimetric assessment—including three replicate dispenses and statistical evaluation—in ≤60 seconds per volume setting
- Universal compatibility: Validates pipettes from any manufacturer across the 10–1000 µL range; supports individual channel verification on multi-channel units
- Automated workflow: Integrated sensor detects pipette tip immersion and initiates sequence; prompts user for three consecutive dispenses without manual timing or volume entry
- ISO 8655-aligned error analysis: Computes both systematic error (bias) and random error (repeatability) using four independent mass measurements per test, reporting % deviation and %CV against nominal volume
- Pass/fail logic engine: Applies configurable acceptance criteria aligned with ISO 8655 Annex B or user-defined limits; visual LED indicators (green/red) provide immediate go/no-go feedback
- Modular validation readiness: Optional Functional Test Kit (sold separately) enables periodic system verification per ISO/IEC 17025 internal quality control requirements
Sample Compatibility & Compliance
SmartCheck is validated for use with aqueous solutions—primarily deionized water at 20 °C—under standard laboratory conditions (20–25 °C, 30–70% RH). Its gravimetric methodology complies with the fundamental principles of ISO 8655-5:2022 (Pipettes — Part 5: Calibration), and its statistical evaluation framework aligns with ISO/IEC 17025:2017 clause 7.7 (Ensuring validity of results). While not a full calibration system, SmartCheck meets the verification frequency and documentation expectations outlined in FDA 21 CFR Part 11 (for electronic records when used with PipetteX), USP (Analytical Instrument Qualification), and EU GMP Annex 15. The device itself is CE-marked and manufactured in accordance with METTLER TOLEDO’s ISO 13485-certified quality management system.
Software & Data Management
The SmartCheck operates standalone for basic verification but integrates seamlessly with Rainin’s PipetteX software (Windows-based, optional installation) for comprehensive data governance. PipetteX captures timestamped test records—including operator ID, pipette serial number, volume setpoint, raw mass values, calculated volume, % error, %CV, and pass/fail status—with automatic generation of PDF reports compliant with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate). Audit trail functionality satisfies 21 CFR Part 11 requirements for electronic signatures and record retention. All data is exportable to CSV or LIMS-compatible formats; no cloud storage is performed by default—data remains on local network drives unless explicitly configured otherwise.
Applications
- Routine pre-use verification prior to critical assays (e.g., qPCR, ELISA, cell culture media preparation) to mitigate sample loss and rework
- Post-maintenance or post-repair functional checks following pipette servicing
- Operator training and technique assessment—real-time feedback reinforces proper aspiration/dispense mechanics
- Supporting IQ/OQ protocols during laboratory instrument qualification projects
- Meeting internal SOP requirements for quarterly or monthly pipette verification in regulated QC/QA environments
- Supplementing formal calibration services by identifying drift between scheduled calibrations
FAQ
How does SmartCheck differ from a full pipette calibration?
SmartCheck performs verification—not calibration. It assesses whether a pipette is performing within predefined tolerance limits using gravimetry; it does not adjust or correct pipette output. Calibration requires traceable standards and adjustment procedures per ISO 8655-6.
Can SmartCheck verify positive-displacement pipettes?
Yes—provided they operate within the 10–1000 µL range and dispense into the SmartCheck reservoir using compatible tips.
Is temperature compensation applied automatically?
Yes. SmartCheck uses built-in ambient temperature and humidity sensors to apply real-time water density and air buoyancy corrections per ISO 8655-5 Annex C.
What happens if a test fails?
The unit displays “FAIL” with red illumination and logs the result. Users should inspect tip fit, technique, environmental stability, and pipette maintenance history before retesting or initiating formal recalibration.
Does SmartCheck require annual recalibration?
No—but periodic system verification using the optional Functional Test Kit is recommended every 6–12 months to confirm balance linearity, sensor response, and algorithm integrity per ISO/IEC 17025 internal QC guidelines.
