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METTLER TOLEDO XPE Precision Balance

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Brand METTLER TOLEDO
Origin Switzerland
Model Variants XPE10001L / XPE10001S / XPE10002S / XPE1202S / XPE1203S
Maximum Capacity 64 kg
Readability 0.001 g
Repeatability 40 mg
Calibration Internal AutoCal™
Ingress Protection IP54
Construction Stainless Steel Frame with Monobloc HighSpeed Sensor
Compliance Fully Supports GLP/GMP, ISO/IEC 17025, USP <41> & <1251>, FDA 21 CFR Part 11 Audit Trail Requirements

Overview

The METTLER TOLEDO XPE Precision Balance is an advanced, high-capacity laboratory balance engineered for demanding weighing tasks across quality control, R&D, and production environments. Built upon the proven Monobloc HighSpeed electromagnetic force compensation sensor architecture, it delivers stable, drift-free measurements from milligram to 64 kg ranges—without compromising on speed or metrological integrity. Unlike conventional precision balances requiring draft shields for sub-gram readability, the XPE series integrates SmartPan™ — a patented dual-compartment weighing pan design that actively dampens air currents and mechanical vibrations. This enables consistent 1 mg readability even in non-ideal conditions (e.g., fume hoods, open benchtops, or HVAC-affected labs), significantly reducing stabilization time by up to 50% compared to previous-generation models. Its IP54-rated enclosure and corrosion-resistant stainless steel frame ensure long-term reliability in laboratories handling aggressive solvents, powders, or aqueous solutions.

Key Features

  • SmartPan™ technology eliminates dependency on draft shields while maintaining 0.001 g readability and improving repeatability by up to 50% (typical repeatability: 40 mg at maximum load)
  • Monobloc HighSpeed sensor provides rapid stabilization—up to 2× faster than prior XPR models—especially critical for high-throughput workflows in regulated environments
  • StatusLight™ visual status indicator offers real-time, color-coded feedback: green (ready), yellow (warning—e.g., leveling or draft interference), red (error—e.g., overload or calibration failure)
  • SmartSens™ infrared motion sensors enable hands-free operation of tare, print, or data transfer functions—reducing cross-contamination risk and enhancing ergonomics
  • ErgoStand™ adjustable height stand promotes neutral posture during extended use, mitigating repetitive strain injury (RSI) risks associated with static benchwork
  • Integrated spill tray allows full disassembly and chemical-resistant cleaning within minutes—supporting strict hygiene protocols in pharmaceutical and food testing labs

Sample Compatibility & Compliance

The XPE series accommodates diverse sample forms—including powders, granules, viscous liquids, and irregular solids—across capacities ranging from 5,000 g to 64,000 g. Its robust mechanical design meets stringent environmental requirements: dust resistance (IP54), chemical splash protection, and thermal stability across ambient temperatures of 10–40 °C. From a regulatory standpoint, the XPE balance is preconfigured to support full compliance with ISO/IEC 17025 accreditation criteria, USP (Balance Performance Verification) and (Weighing on Analytical Balances), as well as FDA 21 CFR Part 11 electronic record and signature requirements when paired with LabX software. All internal calibrations are traceable to national standards via METTLER TOLEDO’s certified AutoCal™ system, ensuring documented metrological continuity for audit readiness.

Software & Data Management

LabX® software serves as the central platform for method-driven weighing, automated data capture, and electronic recordkeeping. Installed directly on the XPE’s integrated touchscreen or deployed server-side, LabX enforces standardized operating procedures (SOPs) through guided user workflows—preventing manual entry errors and enforcing parameter locks (e.g., minimum weight, tolerance limits). It generates fully compliant reports with embedded metadata (operator ID, timestamp, environment logs, calibration history), supports digital signatures, and maintains immutable audit trails per 21 CFR Part 11. Data export options include CSV, PDF, XML, and direct integration with LIMS or ERP systems via ODBC or RESTful API—enabling seamless alignment with enterprise-wide quality management systems.

Applications

  • Pharmaceutical formulation: Accurate dispensing of active pharmaceutical ingredients (APIs) and excipients under GMP-compliant workflows
  • Chemical synthesis: Precise reagent dosing and reaction stoichiometry verification up to 64 kg batch sizes
  • Food & beverage QA/QC: Moisture content determination, recipe scaling, and net weight verification per FDA and EU labeling regulations
  • Materials science: Density determination, ash content analysis, and gravimetric sorption studies requiring high repeatability at elevated loads
  • Environmental testing: Sample preparation for ICP-MS, AAS, or titration where trace-level accuracy must be maintained across wide dynamic ranges

FAQ

What is the difference between XPE and XPR precision balances?

The XPE series replaces the XPR line with enhanced SmartPan™ technology, faster stabilization, improved repeatability, and expanded capacity options—including models rated up to 64 kg—while retaining full backward compatibility with existing LabX methods and accessories.
Does the XPE require external calibration weights?

No. All XPE models feature internal AutoCal™—a motorized, temperature-triggered automatic calibration system that maintains accuracy without manual intervention or external weights.
Can the XPE operate inside a fume hood?

Yes. SmartPan™ technology ensures stable 5–10 mg readability in ventilated enclosures without draft shields, making it ideal for hazardous material handling.
Is LabX software included with the XPE balance?

LabX Basic is pre-installed on the instrument’s touchscreen; LabX Professional requires separate licensing and supports centralized deployment, multi-instrument synchronization, and advanced compliance reporting.
How does the XPE support GLP/GMP documentation requirements?

Through integrated StatusLight™ status logging, automatic calibration records, operator authentication, and full electronic audit trail generation via LabX—ensuring complete traceability from weighing event to final report.

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