Rainin Pipet-Lite XLS+ 8-Channel Manual Pipette
| Brand | Rainin |
|---|---|
| Origin | Switzerland |
| Model | L8-10XLS+ |
| Type | Multichannel Manual Pipette |
| Volume Range | 1–10 µL |
| Accuracy | ±4.0% at 0.04 µL, ±1.5% at 0.075 µL, ±1.0% at 0.1 µL |
| Precision (CV) | ≤3.0% at 0.03 µL, ≤0.6% at 0.03 µL, ≤0.4% at 0.04 µL |
| Increment | 0.02 µL |
| Tip Compatibility | LTS (Lite-Touch System) |
Overview
The Rainin Pipet-Lite XLS+ 8-Channel Manual Pipette is an engineered solution for high-throughput, precision liquid handling in regulated and research-intensive laboratory environments. Designed using advanced mechanical principles and human factors engineering, the XLS+ platform operates on a low-friction piston-seal architecture that minimizes hysteresis and ensures consistent plunger resistance across the full volume range. Unlike conventional air-displacement pipettes, the XLS+ integrates a patented magnetic-assisted plunger system that reduces peak ejection force by up to 35% compared to prior-generation multichannel pipettes—enabling reliable, fatigue-resistant operation during extended workflows such as ELISA plate preparation, qPCR setup, or cell culture passaging. Its lightweight magnesium-alloy body and dynamically balanced center of gravity eliminate torque-induced wrist strain, supporting compliance with ISO 9241-5 ergonomic guidelines for manual handling tools.
Key Features
- Ultra-lightweight construction (up to 35% lighter than predecessor models), reducing operator fatigue during repetitive tasks
- LTS (Lite-Touch System) tip interface ensures secure, leak-free sealing with minimal insertion force and effortless tip ejection—even after repeated autoclaving cycles
- Magnetic-assisted plunger mechanism delivers smooth, linear actuation with reduced peak force and improved tactile feedback
- RFID chip embedded in handle enables GLP/GMP-compliant calibration tracking, service history logging, and inventory management without physical labels or manual entry
- Glove-friendly volume adjustment dial with tactile detents prevents accidental volume drift and supports operation under PPE constraints
- Autoclavable components (up to 121°C, 20 min, 1 bar) including tip ejector and lower housing—validated per ISO 13485 biocompatibility requirements
- High-density polymer tip ejector resistant to chemical degradation, thermal cycling, and mechanical wear
Sample Compatibility & Compliance
The Pipet-Lite XLS+ L8-10XLS+ is validated for use with aqueous buffers, cell suspensions, serum, DNA/RNA solutions, and low-viscosity reagents within its 1–10 µL range. It meets ISO 8655-2:2022 specifications for gravimetric performance testing of piston-operated volumetric apparatus and conforms to ASTM E2758–20 standards for ergonomic evaluation of hand tools. All LTS tips used with this pipette are certified to ISO 8655-6:2022 for tip-pipette compatibility. The integrated RFID system supports 21 CFR Part 11-compliant electronic records when paired with Rainin’s Liquidator Software and approved enterprise IT infrastructure. Full traceability—including calibration dates, technician ID, environmental conditions, and tolerance verification—is maintained through encrypted, tamper-evident data storage.
Software & Data Management
When connected via optional RFID reader and Rainin Liquidator Software (v4.2+), the XLS+ enables automated calibration documentation, user-specific settings synchronization, and audit-ready reporting. Calibration logs include timestamped gravimetric test results, uncertainty budgets per ISO/IEC 17025, and pass/fail status against defined acceptance criteria (e.g., ISO 8655-2 Class A tolerances). The software supports export to CSV, PDF, and XML formats compatible with LIMS and QMS platforms. Audit trails capture all configuration changes, calibration events, and user logins—meeting ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) required for FDA inspections and MHRA audits.
Applications
This 8-channel pipette is optimized for applications demanding high inter-channel consistency and operator endurance: microtiter plate filling (96-well and 384-well formats), serial dilution series in assay development, sample normalization in NGS library prep, immunoblotting reagent dispensing, and high-content screening workflows. Its sub-microliter accuracy at 1 µL supports sensitive applications such as CRISPR guide RNA complex assembly and single-cell lysate transfer. The LTS tip geometry ensures minimal carryover and optimal surface tension interaction—critical for viscous or volatile liquids like glycerol-containing master mixes or DMSO-based compound libraries.
FAQ
Is the L8-10XLS+ compatible with non-Rainin LTS tips?
Yes—any third-party tip meeting ISO 8655-6 LTS dimensional specifications will function reliably, though Rainin-certified tips guarantee full performance validation and warranty coverage.
Can the pipette be sterilized in an autoclave?
The lower assembly (including tip cone, ejector, and shaft) is fully autoclavable at 121°C for 20 minutes; the upper housing and electronics (RFID chip) must be removed prior to sterilization.
What does the RFID chip store?
Calibration date, service interval alerts, user-defined volume presets, last calibration technician ID, and environmental metadata (temperature/humidity during verification).
How is channel-to-channel consistency verified?
Per ISO 8655-2 Annex C, each channel undergoes independent gravimetric testing at three volume points; reported CV values reflect worst-case inter-channel deviation across ten consecutive deliveries.
Does the XLS+ support GLP documentation requirements?
Yes—when used with validated software and documented procedures, it fulfills core GLP elements including instrument identification, calibration traceability, analyst accountability, and raw data integrity per OECD Principles of GLP.
