ROCKER BioVac 630 Six-Position Stainless Steel Filtration Manifold

Overview

The ROCKER BioVac 630 is a precision-engineered six-position stainless steel filtration manifold designed for high-integrity liquid and air sampling applications in regulated life science laboratories. Built entirely from medical-grade SUS316 stainless steel — including the manifold body, individual isolation valves, filter funnels, support plates, handles, and fluidic connectors — the system delivers exceptional corrosion resistance, mechanical durability, and full compatibility with standard sterilization protocols including autoclaving (121 °C, 20 min), dry-heat ovens (up to 250 °C), and direct flame treatment. Its modular architecture supports gravity-fed or vacuum-assisted filtration workflows, operating reliably under vacuum pressures up to –100 kPa and withstanding positive pressure surges up to 3000 psi during integrity testing or backflush procedures. The BioVac 630 is purpose-built for environments requiring repeatable, contamination-free sample processing — particularly in microbiological enumeration (e.g., membrane filtration per ISO 7218, USP , or ASTM D5465), environmental water analysis, pharmaceutical process validation, and bioprocess intermediate monitoring.

Key Features

• Full-SUS316 construction across all wetted and structural components ensures long-term resistance to chloride-induced pitting, acidic/alkaline reagents, and oxidative cleaning agents.
• Patented rotary bayonet locking mechanism (ROCKER Patent No. M381450) enables tool-free, leak-tight coupling of filter cups — eliminating reliance on external clamps and reducing assembly time by >60% versus conventional screw-type manifolds.
• Independent on/off control per position via integrated SUS316 ball valves allows sequential or parallel filtration without cross-contamination risk — critical for multi-sample comparative studies or QC batch testing.
• Universal cup interface accommodates interchangeable 100 mL, 300 mL, and 500 mL SUS316 filter funnels (sold separately or as part of BioVac 631 kit), supporting variable sample volumes while maintaining consistent 47 mm and 50 mm membrane diameters.
• Optimized flow path geometry minimizes dead volume and residue retention; each position provides 9.6 cm² effective filtration area aligned with standardized membrane specifications.
• Compatible with standard 8 mm (5/16″) ID vacuum tubing and common laboratory vacuum sources (e.g., diaphragm pumps, central vacuum systems).

Sample Compatibility & Compliance

The BioVac 630 supports filtration of aqueous, organic, and mildly aggressive solutions across research, clinical, and manufacturing settings. It complies with material requirements outlined in USP (Apparatus for Microbial Testing), ISO 8573-1 (compressed air purity), and FDA 21 CFR Part 11–aligned documentation practices when paired with validated electronic log systems. All stainless steel surfaces meet ASME BPE-2022 surface finish standards (Ra ≤ 0.8 µm) for hygienic design. The manifold is routinely deployed in GLP-compliant environmental labs conducting EPA Method 1603 (E. coli) and Method 1604 (total coliforms), as well as in sterile manufacturing facilities performing filter integrity testing per ASTM F838-22.

Software & Data Management

As a hardware-only filtration platform, the BioVac 630 does not include embedded firmware or proprietary software. However, its mechanical design integrates seamlessly into digital lab ecosystems: valve actuation status can be logged via external pressure transducers or vacuum gauge interfaces; filtration duration and sequence are traceable through LIMS or ELN entries using standardized SOP templates. For audit readiness, the 2-year parts warranty includes documented calibration history of supplied components and full traceability to ROCKER’s ISO 13485-certified manufacturing facility in Taiwan.

Applications

• Membrane filtration for microbial enumeration in drinking water, wastewater, and pharmaceutical water systems.
• Particulate removal and clarification of cell culture supernatants, fermentation broths, and protein solutions prior to HPLC or SEC analysis.
• Airborne microorganism collection using impaction or filtration-based samplers coupled to vacuum manifolds.
• Pre-filtration of solvents and reagents in analytical chemistry labs to prevent HPLC column clogging.
• Validation of sterilizing-grade filters (0.22 µm) under controlled pressure differentials per PDA TR26 guidelines.

FAQ

Is the BioVac 630 compatible with nitrocellulose or PVDF membranes?
Yes — the 47 mm and 50 mm diameter support plates accommodate standard low-protein-binding and hydrophilic/hydrophobic membranes without modification.
Can I use the manifold with corrosive solvents such as acetone or chloroform?
SUS316 offers broad chemical resistance, but prolonged exposure to halogenated solvents may affect elastomeric seals (not present in this all-metal design); verify compatibility per ASTM G128 guidelines for specific solvent–metal interactions.
Does ROCKER provide installation qualification (IQ) or operational qualification (OQ) documentation?
IQ/OQ templates are available upon request for GMP-regulated users; these align with Annex 11 and EU GMP Chapter 4 requirements and include test protocols for valve leak integrity, pressure decay, and dimensional verification.
What is the recommended maintenance interval for the rotary locking mechanism?
No scheduled lubrication is required; periodic visual inspection for debris accumulation and functional verification of rotational torque (≤1.2 N·m) every 6 months is advised in high-throughput labs.
Are replacement valves or gaskets available as spare parts?
All valve assemblies and sealing components are field-replaceable; part numbers are listed in the ROCKER Technical Support Portal (support.rocker.com.tw) under BioVac 630 Maintenance Kits.