Shanghai Yarong RE-5205A Rotary Evaporator

Overview

The Shanghai Yarong RE-5205A Rotary Evaporator is an engineered benchtop purification system designed for efficient solvent removal, concentration, and recovery under reduced pressure. Based on the principle of rotary evaporation—where a rotating flask increases surface area while vacuum lowers the boiling point of solvents—the RE-5205A enables gentle, reproducible processing of thermally sensitive compounds. Its integrated digital control system provides real-time monitoring and precise regulation of rotational speed and bath temperature, ensuring consistent vaporization kinetics across diverse sample matrices. The unit is constructed with corrosion-resistant stainless steel components and borosilicate glassware (standard 5L evaporation flask, vertical condenser, and receiving flask), supporting routine operation in academic research labs, QC/QA environments, and pilot-scale process development.

Key Features

• Digital dual-display interface showing real-time rotation speed (0–120 rpm) and water/oil bath temperature (ambient to 99 °C) with ±1 °C accuracy
• Motor-driven automatic lifting mechanism for safe, repeatable flask positioning—reducing manual handling and thermal shock risk during condensate collection
• Top-entry vacuum condenser design with 0.4 m² effective cooling surface area, optimized for high-efficiency reflux and minimal bumping
• Stainless steel heating bath with PTFE-coated immersion heater and over-temperature cutoff protection
• Sealed vacuum system compatible with standard diaphragm or rotary vane vacuum pumps (recommended ultimate vacuum ≤10 mbar)
• Borosilicate glass assembly conforming to ISO 3585 specifications; all joints feature standardized ISO 29/32 and ISO 24/29 taper interfaces

Sample Compatibility & Compliance

The RE-5205A accommodates a broad range of organic solvents (e.g., ethanol, acetone, ethyl acetate, dichloromethane) and aqueous solutions commonly used in natural product extraction, pharmaceutical intermediate purification, and polymer synthesis. Its 5 L evaporation capacity supports batch processing from 1–4 L working volume, balancing throughput and control. While not certified to specific regulatory standards as a standalone device, the system’s design aligns with general laboratory safety and operational requirements outlined in ISO/IEC 17025:2017 (clause 6.4 on equipment suitability) and supports GLP-compliant workflows when integrated into validated SOPs. All glass components are traceable by batch number; documentation includes CE-marked electrical safety certification per IEC 61010-1.

Software & Data Management

The RE-5205A operates via embedded microcontroller logic without external software dependency. All operational parameters are logged locally on the front-panel display but are not stored or exportable—consistent with Class I laboratory instrumentation per IEC 62304. For laboratories requiring audit trails or electronic records, integration with third-party data acquisition systems (e.g., LabVIEW or custom SCADA) is feasible via analog 0–10 V output signals for temperature and speed (available upon request with optional interface module). No built-in network connectivity or FDA 21 CFR Part 11 compliance is provided; users implementing electronic recordkeeping must validate their own configuration per ALCOA+ principles.

Applications

• Concentration of heat-labile biomolecules (e.g., peptides, enzymes, plant extracts) in biopharmaceutical R&D
• Solvent recovery and residue isolation in fine chemical synthesis and catalyst recycling
• Preparative-scale dehydration of hygroscopic intermediates prior to crystallization
• Removal of low-boiling solvents following column chromatography or solid-phase extraction
• Standardized evaporation protocols compliant with USP dissolution apparatus auxiliary methods and ASTM D129-18 for volatile content determination

FAQ

What vacuum level is recommended for optimal performance with the RE-5205A?
A stable vacuum between 10–50 mbar is typically sufficient for most common solvents; lower pressures may be required for high-boiling-point solvents (>150 °C at ambient pressure), though bath temperature must be adjusted accordingly to avoid decomposition.
Is the heating bath compatible with silicone oil or only water?
Yes—the bath is rated for both water and heat-transfer oils up to 180 °C; however, maximum operating temperature remains limited to 99 °C per the controller specification.
Can the RE-5205A be operated continuously for extended periods?
Continuous operation is supported under nominal load conditions (≤3 L solvent, ≤60 °C bath, ≤80 rpm); thermal duty cycle should include ≥15-minute cooldown intervals after 4 hours of uninterrupted use to maintain long-term motor and seal integrity.
Are replacement glass parts available with ISO-standard taper dimensions?
Yes—all glassware—including 5 L evaporation flasks, condensers, and receiving flasks—is manufactured to ISO 29/32 (main joint) and ISO 24/29 (auxiliary ports) tolerances, ensuring interchangeability with major OEM and third-party accessories.
Does the unit include a vacuum controller or pressure sensor?
No—the RE-5205A does not integrate vacuum sensing or regulation; external vacuum controllers (e.g., Vacuubrand VRD or KNF NVP series) must be connected upstream for automated pressure modulation.