Shanghai Yarong RE-52CS Rotary Evaporator

Overview

The Shanghai Yarong RE-52CS Rotary Evaporator is an entry-level yet robust benchtop purification system engineered for reliable solvent removal, concentration, and gentle compound recovery under reduced pressure. Based on the fundamental principle of rotary evaporation—where a rotating flask increases surface area and promotes uniform thin-film formation while vacuum lowers boiling points—the RE-52CS delivers consistent performance in academic labs, pilot-scale R&D, and quality control environments. Its integrated design features a vertical coil condenser with a total heat exchange surface area of 0.08 m², supplemented by a dedicated dry-ice cooling interface to enhance condensate recovery efficiency for low-boiling or volatile solvents (e.g., diethyl ether, dichloromethane, pentane). The system operates within a controlled temperature range from ambient to 99 °C with ±1 °C accuracy, ensuring thermal stability during extended distillation cycles.

Key Features

• Digitally displayed thermostatic heating bath with precise PID-based temperature regulation and real-time readout
• Stepless electronic speed control (0–130 rpm) enabling optimized film thickness and evaporation kinetics across diverse viscosities
• Vertical coil condenser with high-efficiency copper-alloy tubing and optimized coolant path geometry
• Dedicated dry-ice cooling port adjacent to the condenser jacket, supporting sub-zero condensation without external cryocoolers
• Sealed vacuum interface compatible with standard lab-grade diaphragm or oil-sealed vacuum pumps (recommended ultimate vacuum ≤10 mbar)
• Borosilicate glass construction (GG-17) for all major components—including 2 L evaporation flask, receiving flask, condenser, and vapor duct—ensuring chemical resistance and thermal shock tolerance
• Integrated lift mechanism with manual height adjustment for safe flask immersion and removal

Sample Compatibility & Compliance

The RE-52CS accommodates standard 24/29 and 29/32 ground-glass joints, permitting seamless integration with common laboratory glassware such as round-bottom flasks, Hickman stills, and cold-finger adapters. It supports aqueous, organic, and mildly corrosive solvent systems (e.g., methanol, acetone, ethyl acetate, toluene), though prolonged exposure to strong acids or halogenated solvents above 60 °C requires optional PTFE-coated seals. While not certified to ISO/IEC 17025 or GLP-compliant validation protocols out-of-the-box, the instrument’s repeatable temperature and rotation control enables method transfer and documentation in accordance with internal SOPs aligned with ASTM E2654 (Standard Guide for Validation of Analytical Methods) and USP (Analytical Instrument Qualification). Routine calibration of the digital temperature sensor and tachometer is recommended per lab quality management procedures.

Software & Data Management

The RE-52CS operates as a standalone analog-digital hybrid instrument without embedded firmware or network connectivity. All operational parameters—bath temperature setpoint, actual reading, and rotational speed—are monitored via front-panel LED displays. No proprietary software, data logging, or USB/RS-232 interfaces are included; however, external digital thermometers and tachometers may be employed for independent verification and manual logbook entries. For laboratories implementing electronic lab notebooks (ELNs) or LIMS integration, parameter tracking must be performed manually or via third-party environmental monitoring systems interfaced through analog voltage outputs (if retrofitted). The absence of audit trail functionality means it is not compliant with FDA 21 CFR Part 11 requirements unless paired with validated external recording hardware and procedural controls.

Applications

• Solvent removal from natural product extracts in phytochemistry and herbal medicine research
• Concentration of reaction mixtures post-Suzuki or Heck coupling in synthetic organic chemistry
• Recovery of heat-sensitive active pharmaceutical ingredients (APIs) during early-stage process development
• Preparative-scale dehydration of hygroscopic intermediates in fine chemical synthesis
• Crystallization initiation via controlled supersaturation in salt screening studies
• Removal of residual solvents from polymer solutions prior to GPC analysis or film casting

FAQ

What vacuum level is recommended for optimal operation?
A stable vacuum between 10–50 mbar is typically sufficient for most applications; lower pressures (<5 mbar) may increase bumping risk with viscous or foaming samples.
Is the B-220 water bath included with the RE-52CS?
No—the B-220 constant-temperature water bath is a separate accessory unit manufactured by Shanghai Yarong and must be ordered independently.
Can the RE-52CS be used with corrosive solvents like concentrated HCl or bromine?
Not without modification; standard GG-17 glass and silicone/viton seals are incompatible with strong oxidizers or halogens at elevated temperatures—PTFE-lined joints and specialized gaskets are required.
What maintenance intervals are advised for long-term reliability?
Daily visual inspection of seals and glass integrity; monthly cleaning of condenser coils with ethanol or isopropanol; annual verification of temperature sensor calibration using a traceable reference thermometer.
Does the unit support inert gas purging (e.g., nitrogen sweep)?
Yes—the vapor duct includes a standard 6 mm O.D. inlet port suitable for nitrogen line connection, enabling oxygen-sensitive evaporation protocols.