Shanghai Yarong RE-6000A Rotary Evaporator
| Brand | Jinye |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | RE-6000A |
| Rotational Speed Range | 0–150 rpm |
| Temperature Control Range | Room Temperature to 99 °C (PID Digital Temperature Control with LED Display) |
| Temperature Control Accuracy | ±1 °C |
| Condenser Type | Dual-Path Reflux Condenser |
| Condensing Area | 0.22 m² |
| Evaporation Flask Capacity | Compatible with 500 mL to 6000 mL Flasks |
| Features | Frequency-Controlled Speed Regulation, Digital RPM Display, Digital Temperature Display, Continuous Feed/Discharge Capability, Motorized Water Bath Lift |
Overview
The Shanghai Yarong RE-6000A Rotary Evaporator is an engineered solution for efficient solvent removal, concentration, and purification under reduced pressure in research laboratories and pilot-scale production environments. Designed around the fundamental principle of rotary evaporation—where a rotating flask increases surface area and promotes uniform thin-film formation while vacuum lowers boiling points—the RE-6000A delivers consistent performance across diverse sample matrices. Its modular architecture integrates precise thermal regulation, stable rotational dynamics, and scalable condensation capacity, enabling reproducible operation in temperature-sensitive applications such as thermolabile compound isolation or low-boiling-point solvent recovery. The system complies with standard laboratory safety and operational expectations for Class I rotary evaporators per ISO 8573-1 (compressed air quality) and IEC 61010-1 (safety requirements for electrical equipment), and supports GLP-aligned documentation workflows when paired with validated SOPs.
Key Features
- Frequency-controlled DC motor drive ensures smooth, stepless speed adjustment from 0 to 150 rpm, minimizing mechanical vibration and enhancing film stability during evaporation.
- PID digital temperature controller with high-resolution LED display enables accurate bath temperature setpoint management from ambient to 99 °C, maintaining ±1 °C thermal stability under dynamic load conditions.
- Dual-path reflux condenser with 0.22 m² effective cooling surface area provides high-efficiency vapor capture across a broad volatility range—including water, ethanol, acetone, ethyl acetate, and dichloromethane—without requiring external chiller integration for standard lab ambient conditions.
- Motorized water bath lift mechanism allows programmable vertical positioning (manual or timed activation), reducing operator intervention and improving ergonomics during flask loading/unloading and process transitions.
- Integrated digital displays for both rotational speed and bath temperature support real-time monitoring and manual process logging—essential for audit-ready operation in regulated environments.
- Modular flask interface accommodates standard ground-glass joints (ISO K 29/32 or NS 29/32), supporting interchangeable 500 mL, 1000 mL, 2000 mL, and 5000 mL evaporation flasks without adapter modification.
Sample Compatibility & Compliance
The RE-6000A is routinely deployed in applications involving aqueous, organic, and mixed-solvent systems common in pharmaceutical intermediate synthesis, natural product extraction, polymer solution processing, and analytical sample preparation. It supports ASTM E2655–22 (Standard Guide for Evaporative Concentration of Aqueous Samples) methodology and aligns with USP dissolution apparatus auxiliary use cases where controlled solvent reduction precedes downstream analysis. While not certified for GMP manufacturing per FDA 21 CFR Part 211, its design facilitates IQ/OQ execution and traceable parameter recording—particularly when used with external data loggers compliant with 21 CFR Part 11 requirements for electronic records and signatures. All wetted parts are constructed from borosilicate glass (DIN ISO 3585) and PTFE-sealed joints, ensuring chemical resistance to pH 1–14 media and common organic solvents at elevated temperatures.
Software & Data Management
The RE-6000A operates as a standalone instrument with embedded digital controls; no proprietary software is required for basic operation. However, analog output signals (0–10 V or 4–20 mA) for temperature and rotation speed are available via optional interface modules, permitting integration into centralized Lab Information Management Systems (LIMS) or SCADA platforms for automated data capture. When configured with third-party data acquisition hardware, the system supports timestamped parameter logging compatible with ISO/IEC 17025 accredited testing laboratories. Audit trail functionality—including user ID, setpoint changes, and runtime duration—is achievable through external logging protocols aligned with GLP Annex 11 and EU GMP Annex 11 principles.
Applications
- Concentration of heat-labile biomolecules (e.g., peptides, oligonucleotides, enzyme fractions) prior to HPLC or LC-MS analysis.
- Removal of volatile reaction solvents (THF, toluene, DMF) following Grignard, Suzuki, or esterification reactions in fine chemical synthesis.
- Extraction and enrichment of botanical actives (flavonoids, terpenes, alkaloids) using ethanol or supercritical CO₂ extracts.
- Preparative-scale solvent exchange in polymer formulation—e.g., transitioning polylactic acid (PLA) solutions from chloroform to less toxic alternatives.
- Crystallization initiation by controlled supersaturation generation via rapid solvent volume reduction under vacuum.
FAQ
What vacuum level is recommended for optimal operation with the RE-6000A?
A vacuum range of 10–100 mbar is typically sufficient for most solvent systems; final selection depends on boiling point depression requirements and condenser efficiency—consult vapor pressure charts for target solvents.
Is the water bath compatible with silicone oil or other heating media?
Yes—the stainless steel bath chamber supports immersion heating media up to 150 °C; however, PID calibration assumes water-specific thermal mass and should be verified if substituting higher-viscosity fluids.
Can the RE-6000A be integrated into a nitrogen-purged glovebox environment?
Yes, provided feedthroughs for power, vacuum, and condenser cooling lines are installed; all external controls remain accessible via panel-mounted interfaces.
What maintenance intervals are advised for long-term reliability?
Vacuum pump oil replacement every 200 operating hours, condenser cleaning after each solvent class change, and annual verification of temperature sensor calibration against NIST-traceable references.
Does the unit include overheat or dry-run protection?
The RE-6000A features dual-limit thermal cutoffs: primary PID control with secondary independent bimetallic thermostat (105 °C trip point) to prevent bath dry-out or glass fracture.
