Shimadzu HS-20 / HS-20LT / HS-20 TRAP (90-Position) Used Automatic Headspace Sampler

Overview

The Shimadzu HS-20 series automatic headspace sampler is a precision-engineered, laboratory-grade instrument designed for reliable and reproducible analysis of volatile organic compounds (VOCs) in solid, liquid, or semi-solid matrices. Based on the equilibrium headspace gas-phase extraction principle—where analytes partition between the sample matrix and the overlying vapor phase—the HS-20 series enables quantitative transfer of headspace vapors into a gas chromatograph (GC) via either quantitative loop injection (HS-20/HS-20LT) or cryogenically focused cold trap injection (HS-20 TRAP). This dual-mode architecture supports method flexibility across regulatory and research applications, including residual solvent analysis (ICH Q3C), environmental monitoring (EPA Method 502.2, 624), pharmaceutical stability testing, and food flavor profiling. Units offered are original Shimadzu-manufactured instruments imported from Japan, fully refurbished and functionally validated to meet operational specifications consistent with factory performance benchmarks.

Key Features

• Dual-Mode Sampling Architecture: Supports both quantitative loop (HS-20/HS-20LT) and cryogenic cold trap (HS-20 TRAP) configurations—enabling trace-level detection down to sub-ppbv ranges when coupled with high-sensitivity GC detectors (e.g., FID, ECD, or MS).
• High Reproducibility: Engineered for ≤1.5% RSD (relative standard deviation) in peak area across 90-position sample sequences under standardized temperature equilibration protocols (e.g., 60°C, 30 min).
• Minimal Carryover: Integrated bake-out cycles, inert flow path materials (silco-treated stainless steel and fused silica), and programmable needle purge ensure cross-contamination <0.05% between sequential samples.
• Thermal Robustness: Capable of equilibration temperatures up to 200°C and transfer line heating to 220°C—validated for high-boiling-point analytes such as chlorinated benzenes, nitroaromatics, and plasticizers.
• User-Centric Mechanical Design: Ergonomic 90-vial carousel accommodates standard 20 mL headspace vials with crimp caps; tool-free access to syringe, valve manifold, and oven chamber simplifies routine maintenance and cleaning.

Sample Compatibility & Compliance

The HS-20 series accepts standard 20 mL headspace vials with magnetic crimp seals and is compatible with common GC autosampler trays (e.g., Agilent 7890/8890, Thermo ISQ, Shimadzu GC-2010/GC-2030). It supports aqueous, organic, polymer, soil, and biological matrices without derivatization. Instrument operation adheres to key analytical standards including ISO 17025–compliant validation frameworks, USP for residual solvents, and ASTM D7622 for VOC determination in water. When deployed in regulated environments, the system supports audit-trail-enabled method storage (via optional PC control software), electronic signature compatibility, and alignment with FDA 21 CFR Part 11 requirements when integrated with compliant LIMS or chromatography data systems (CDS).

Software & Data Management

The HS-20 operates via Shimadzu’s GC solution software (e.g., GCsolution or LabSolutions), enabling full remote configuration of equilibration time/temperature, pressurization parameters, loop fill/flush cycles, trap cooling/focusing, and thermal desorption profiles. All method parameters—including vial position mapping, sequence logs, and error codes—are timestamped and exportable in CSV or XML format. Firmware versions are verified against Shimadzu’s official release notes; no third-party firmware modifications are applied. Refurbished units include updated firmware (v3.30 or later) and are preconfigured for seamless handshake with GC systems using Shimadzu’s proprietary communication protocol (RS-232 or Ethernet).

Applications

• Residual solvent quantification in active pharmaceutical ingredients (APIs) and excipients per ICH Q3C guidelines
• VOC emissions profiling from packaging materials (e.g., PET bottles, laminated films)
• Environmental analysis of BTEX, chlorinated ethenes, and trihalomethanes in groundwater and wastewater
• Flavor and fragrance compound profiling in beverages, dairy products, and fermented foods
• Quality control of polymer additives (e.g., plasticizers, antioxidants) via headspace-GC/FID
• Forensic toxicology screening for volatile intoxicants (e.g., ethanol, acetone, isopropanol)

FAQ

Is this unit certified for use in GLP or GMP laboratories?
Yes—refurbishment includes functional verification per Shimadzu’s OEM test protocols, calibration certificate documentation, and optional IQ/OQ support packages aligned with ISO/IEC 17025 and Annex 11 expectations.
What maintenance history is available for each unit?
Each instrument is accompanied by a refurbishment dossier detailing replaced components (e.g., syringe, valves, O-rings), thermal calibration records, and leak-test results conducted at 100 kPa pressure hold for ≥5 minutes.
Can the HS-20 TRAP mode be retrofitted onto an HS-20LT unit?
No—cold trap functionality requires dedicated hardware (Peltier-cooled trap assembly, cryo-valve manifold, and modified GC interface); only factory-built HS-20 TRAP units support this mode.
Are spare parts and consumables still supported by Shimadzu?
Yes—Shimadzu continues to supply genuine parts (P/Ns: 228-57205-91, 228-57206-91, 228-57207-91) and consumables (vial caps, septa, loop liners) globally through authorized channels.
Does the unit include GC interface tubing and fittings?
Yes—all refurbished units ship with Shimadzu-certified transfer lines (0.53 mm ID fused silica), Swagelok fittings, and GC inlet adapters compatible with standard split/splitless injectors.