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| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TCS SP8 |
| Type | Laser Scanning Confocal Microscope |
| Optical Architecture | Upright or Inverted Configurable Platform |
| Detection Principle | Point-scanning confocal fluorescence imaging with spectral detection and time-gated photon counting capability |
| Maximum Frame Rate | 428 fps (at 512 × 32 resolution) |
| Field of View | Up to 22 mm diagonal (with resonant scanner and wide-field optics) |
| Scan Modes | Galvoscanner, Resonant Scanner, Galvoflow (combined galvo-resonant hybrid mode for accelerated Z-stack acquisition) |
| Detector Options | Hybrid Detectors (HyD), PMTs, Spectral Detectors (Tuneable Bandpass or Linear Unmixing) |
| Excitation Sources | Integrated white-light laser (WLL, 470–670 nm), optional UV/IR lasers, acousto-optic tunable filters (AOTF) |
| Software Platform | LAS X (v3.7+), compliant with FDA 21 CFR Part 11 audit trail and electronic signature modules |
| Compliance | CE, IEC 61000-6-3, ISO 13485 (for medical device configurations), GLP/GMP-ready metadata logging |
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