Optical Instruments
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| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | STELLARIS 8 DIVE |
| Instrument Type | Point-Scanning Confocal Microscope |
| Excitation Range | Up to 1300 nm |
| Detection Range | 380–800 nm (tunable via 4Tune spectral detector) |
| Core Technology | Tunable non-descanned spectral detection with variable beam expander (VBE) |
| Compliance | Designed for GLP/GMP-aligned workflows |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | STELLARIS 8 FALCON |
| Imaging Modality | Time-Correlated Single-Photon Counting (TCSPC)-based Fluorescence Lifetime Imaging (FLIM) |
| Frame Rate | Up to 4 fps at 256 × 256 pixels |
| Spectral Channels | Simultaneous acquisition across up to 4 spectral detection channels or sequential acquisition across up to 10 channels |
| FLIM Analysis Modes | Biexponential decay fitting, phasor plot analysis, spectral-FLIM unmixing |
| Software Integration | Fully embedded in Leica LAS X NAVIGATOR and LAS X LITE platforms |
| Compliance | Designed for GLP/GMP-aligned workflows |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Instrument Type | Point-Scanning Confocal Microscope |
| Model | STELLARIS |
| Detection Range | 410–850 nm |
| Excitation Source | White Light Laser (WLL), up to 8 simultaneous spectral lines |
| Detector Technology | Power HyD hybrid detectors |
| Core Capabilities | Fluorescence Lifetime Imaging (FLIM), TauSense-based functional contrast, AI-driven rare-event detection (Aivia), 3D optical sectioning, multi-modal integration (STED, DIVE, DLS, FALCON, CARS) |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Instrument Type | Point-Scanning Confocal Microscope |
| Laser Source | 8-line tunable white light laser (440–790 nm) |
| Detector | Power HyD hybrid detector series |
| Spectral Detection Range | 410–850 nm |
| Fluorescence Lifetime Imaging (FLIM) Capability | TauSense suite (TauContrast, TauGating, TauSeparation, TauInteraction) |
| Resolution Enhancement | LIGHTNING super-resolution engine with Dynamic Signal Enhancement (DSE) and AiviaMotion AI-accelerated real-time processing |
| Software Platform | LAS X Navigator + Aivia AI-powered analysis suite |
| Compliance | Designed for GLP/GMP-aligned workflows |
| Optical Architecture | Integrated acousto-optical beam splitter (AOBS), optimized light path, and photon arrival time digitization at pixel level (16 time-gated channels) |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | STELLARIS CRS |
| Instrument Type | Point-Scanning Confocal Microscope |
| Excitation | Near-Infrared (NIR) Lasers |
| Imaging Modalities | Stimulated Raman Scattering (SRS), Coherent Anti-Stokes Raman Scattering (CARS), Multiphoton Fluorescence, Second Harmonic Generation (SHG), FLIM |
| Spatial Resolution | Subcellular (≤ 300 nm lateral, ≤ 1 µm axial) |
| Detection | Spectral Unmixing, TauSense Lifetime-Gated Acquisition |
| Software Platform | LAS X with ImageCompass Interface |
| Compliance | Designed for GLP/GMP-aligned workflows |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | STELLARIS Cryo |
| Application Domain | Cryo-Correlative Light and Electron Microscopy (Cryo-CLEM) |
| Cooling Stage | Integrated Liquid Nitrogen–Cooled Stage with Transfer Shuttle |
| Software Platform | LAS X Coral Cryo (with TauSense, LIGHTNING, and Interpolated 3D Targeting) |
| Objective Lens | HC PL APO 50×/0.90 Cryo-Optimized Dry Objective |
| Detection System | Power HyD Hybrid Detectors |
| Light Source | White Light Laser (WLL, 470–670 nm) |
| Imaging Modes | Confocal Reflectance, Fluorescence, TauContrast, TauSeparation, Spectral Unmixing |
| Ice Thickness Assessment | Dual-mode (Overview + Confocal Reflectance Z-Stack) |
| Data Format | Open, Metadata-Rich TIFF & HDF5 (CF-1 compliant) |
| Regulatory Alignment | Designed for GLP/GMP-aligned workflows |
| Brand | Leica |
|---|---|
| Country of Origin | Germany |
| Model | STELLARIS DLS |
| Instrument Type | Point-Scanning Confocal Microscope with Integrated Digital Light Sheet Module |
| Integration Compatibility | STELLARIS 5 and STELLARIS 8 platforms |
| Optical Architecture | Inverted microscope with vertical dual-axis light sheet generation via TwinFlect mirror system |
| Illumination | Scanned Gaussian or top-hat light sheet (405–785 nm excitation range) |
| Detection | Dual sCMOS cameras (optional high-speed or high-sensitivity configuration) |
| Sample Mounting | Standard glass-bottom dishes, U-shaped capillaries, FEP tubing, or custom mounting frames (24 × 50 mm rectangular / Ø30 mm circular) |
| Refractive Index Matching | Compatible with water, glycerol, BABB, Scale, CUBIC, and other clearing media |
| Software Platform | LAS X LightSheet Wizard with real-time fusion, environmental control module, 3D Visualization, and GLP-compliant audit trail (21 CFR Part 11 ready) |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Instrument Type | Point-Scanning Confocal Microscope |
| Model | STELLARIS SpectraPlex |
| Spectral Unmixing Capacity | >15 fluorophores per acquisition |
| Workflow Integration | Aivia AI-powered analysis platform |
| Compliance | Designed for GLP/GMP-aligned spatial biology workflows, compatible with ISO 13485–informed documentation practices |
| Brand | Leica |
|---|---|
| Country of Origin | Germany |
| Model | Leica STELLARIS STED |
| Instrument Type | Point-Scanning Confocal Microscope |
| STED Laser Wavelengths | 592 nm, 660 nm, 775 nm |
| Excitation Range | 440–790 nm (White Light Laser) |
| Detection | Up to 5 spectral Power HyD detectors (HyD S/X/R), 1.5 ns system dead time |
| Objective Support | STED-optimized STED WHITE 100× oil, 93× glycerol (motCORR), 86× water (motCORR) |
| Resolution | <30 nm lateral, <100 nm axial (sample- and fluorophore-dependent) |
| Core Technology | Time-gated STED (TauSTED Xtend), TauSense-enabled lifetime discrimination, FLIM-capable with FALCON module |
| Software Platform | LAS X with ImageCompass, LAS X Navigator, TauSense tools |
| Brand | Leica |
|---|---|
| Country of Origin | Germany |
| Model | STELLARIS STED |
| Excitation Wavelength Range | 440–790 nm (White Light Laser) |
| STED Depletion Wavelengths | 592 nm, 660 nm, 775 nm |
| Spatial Resolution | <30 nm (lateral), <100 nm (axial), sample- and fluorophore-dependent |
| Detection | Up to 5 spectral Power HyD detectors with 1.5 ns system dead time |
| Objective Options | STED WHITE 100× oil, 93× glycerol (motCORR), 86× water (motCORR) |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Motorized XY Translation Stage |
| Pricing | Upon Request |
| Brand | Leica Microsystems |
|---|---|
| Origin | Germany |
| Model | Leica Structured Illumination (OptiGrid® Module) |
| Compatibility | Integrated with Leica DM6 B, DMi8, and other upright/inverted research-grade microscopes |
| Illumination Technology | Grid-based optical sectioning via patterned illumination and computational reconstruction |
| Software Platform | Leica Application Suite X (LAS X) with MM AF module |
| Regulatory Compliance | CE-marked, compliant with ISO 13485 manufacturing standards for medical device–related instrumentation |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | Swingarm Stands |
| Type | Modular Counterbalanced Stereo Microscope Support System |
| Compliance | Designed for ISO 13715 (Ergonomics of Visual Display Terminals) and DIN EN 61326-1 (EMC for Laboratory Equipment) |
| Vibration Damping | Up to 50% reduction vs. standard rigid feet |
| Motion Mechanism | Rack-and-pinion vertical adjustment (heavy-duty variant), precision ball-bearing horizontal arm |
| Lubrication-Free Vertical Guidance | Yes |
| Mounting Interface | Standard M6/M8 threaded holes, compatible with Leica Z6/Z16/Z30 stereo microscope bodies and third-party C-mount adapters |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TCS SP8 CARS |
| Laser Modalities | Visible, UV, IR, SHG, CARS |
| Imaging Modes | Single-photon fluorescence, multiphoton fluorescence, CARS, SHG, spectral unmixing |
| Scan Systems | Dual scanning architecture (standard resonant + high-speed resonant/galvo) |
| Software Platform | LAS X (successor to LAS AF), FDA 21 CFR Part 11 compliant modules available |
| Compliance | ISO 13485–certified manufacturing, CE-marked, GLP/GMP-ready audit trail support |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TCS SP8 DLS |
| Imaging Principle | Orthogonal light-sheet illumination integrated with confocal detection |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TCS SP8 |
| Type | Laser Scanning Confocal Microscope |
| Optical Architecture | Upright or Inverted Configurable Platform |
| Detection Principle | Point-scanning confocal fluorescence imaging with spectral detection and time-gated photon counting capability |
| Maximum Frame Rate | 428 fps (at 512 × 32 resolution) |
| Field of View | Up to 22 mm diagonal (with resonant scanner and wide-field optics) |
| Scan Modes | Galvoscanner, Resonant Scanner, Galvoflow (combined galvo-resonant hybrid mode for accelerated Z-stack acquisition) |
| Detector Options | Hybrid Detectors (HyD), PMTs, Spectral Detectors (Tuneable Bandpass or Linear Unmixing) |
| Excitation Sources | Integrated white-light laser (WLL, 470–670 nm), optional UV/IR lasers, acousto-optic tunable filters (AOTF) |
| Software Platform | LAS X (v3.7+), compliant with FDA 21 CFR Part 11 audit trail and electronic signature modules |
| Compliance | CE, IEC 61000-6-3, ISO 13485 (for medical device configurations), GLP/GMP-ready metadata logging |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TCS SP8 MP |
| Instrument Type | Point-Scanning Multiphoton Confocal Microscope |
| Excitation Range | 680–1300 nm |
| Maximum IR Wavelength | 1300 nm |
| Resonant Scanner Speed | 8 kHz / 12 kHz |
| Field of View (FOV) | up to 22 mm |
| Detection | Leica HyD NDD & HyD RLD non-descanned detectors |
| Objective Correction | motCORR electrically adjustable correction collar |
| Specialized Objectives | HC IRAPO L 25×/1.00 W motCORR, HC FLUOTAR L 25×/1.00 IMM (ne=1.457) motCORR VISIR, APO HCX L20×/0.95 IMM for BABB immersion (ne=1.559) |
| Software Platform | LAS X with integrated multiphoton control, FLIM wizard, and STED/FLIM/SMD module compatibility |
| Compliance | Designed for GLP/GMP-aligned workflows |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TCS SP8 SMD |
| Application Domain | Single-Molecule Detection (SMD), Fluorescence Correlation Spectroscopy (FCS), Fluorescence Cross-Correlation Spectroscopy (FCCS), Fluorescence Lifetime Imaging Microscopy (FLIM), Fluorescence Lifetime Correlation Spectroscopy (FLCS) |
| Integrated Hardware Platform | PicoQuant MD-series detection modules and timing electronics |
| Software Integration | PicoQuant SymPhoTime 64 (SMD-optimized edition) |
| Optical Architecture | Inverted confocal platform with tunable white-light laser (WLL), spectral detection (HyD detectors), and time-correlated single-photon counting (TCSPC) capability |
| Compliance | Designed for GLP/GMP-aligned workflows |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TCS SP8 X |
| Excitation Source | Tunable White Light Laser (WLL), Pulsed |
| Detection Channels | Up to 5 Spectral Detection Channels |
| Excitation Lines | Up to 8 Simultaneous Lines |
| FLIM Compatibility | Yes, with Adjustable Repetition Rate via Pulse Picker |
| LightGate Technology | Time-Gated Spectral Detection |
| Spectral Resolution | Continuous Excitation & Emission Acquisition (Excitation–Emission Matrix Mapping) |
| Application Scope | Live-Cell Imaging, Multicolor Fluorescence, Spectral Unmixing, FLIM, pH/Binding Microenvironment Analysis |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TCS SP8 X |
| Excitation Source | Tunable White Light Laser (WLL), Pulsed |
| Detection | Spectral Detection with Adjustable Bandpass, Up to 8 Simultaneous Excitation Lines |
| Fluorescence Lifetime Imaging (FLIM) Capability | Yes |
| Scan Mode | Galvo + Resonant Scanner |
| Zoom Optics | Continuous Spectral Zoom (λ-Zoom) |
| Microscope Frame | Inverted or Upright Configurable Platform |
| Vibration Isolation | Compatible with Active Damping Optical Tables |
| Software | LAS X Professional Suite with Spectral Unmixing, FLIM Analysis, and GLP-Compliant Audit Trail Modules |
| Compliance | Designed for ISO 13485-aligned workflows |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | THUNDER Imager 3D Live Cell |
| Core Technology | Computational Clearing (real-time deconvolution for widefield fluorescence) |
| Imaging Modality | High-sensitivity widefield fluorescence microscopy with integrated environmental control |
| Camera | DFC9000 GTC sCMOS (QE up to 82%) |
| Illumination | Multi-line high-intensity LED source with narrow excitation bandwidths |
| Stage | Quantum motorized stage (≤ ±0.25 µm reproducibility |
| Focus Control | Adaptive Focus Control (AFC) + closed-loop Z-drive (20 nm repeatability) |
| Throughput | Up to 90 fps full-frame acquisition |
| Z-stack Speed | 150-layer stack in <60 s |
| Environmental Chamber | Integrated CO₂, temperature & humidity control with micro-humidifier for long-term live imaging |
| Software Platform | LAS X (GLP-compliant, audit trail enabled, FDA 21 CFR Part 11 ready) |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | THUNDER Imager Cell Spinning Disk System |
| Category | Spinning Disk Confocal Microscopy Platform for 3D Live-Cell and Thick-Tissue Imaging |
| Compliance | Designed for GLP/GMP-adjacent research environments |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | THUNDER |
| Imaging Principle | Widefield Fluorescence with Real-Time Computational Clearing |
| Compliance | ISO/IEC 2382:2015 (Information Technology — Vocabulary), GLP/GMP-Ready Data Integrity Architecture |
| Software Platform | Leica Application Suite X (LAS X) v4.13+ |
| Data Handling | Native Support for TIFF, OME-TIFF, HDF5 |
| Regulatory Context | Designed for 21 CFR Part 11–compliant environments with optional audit trail and electronic signature modules |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TL3000 Ergo and TL5000 Ergo |
| Numerical Aperture (NA) | 0.73 (TL3000 Ergo), 0.9 (TL5000 Ergo) |
| Illumination | High-stability white LED |
| Contrast Modes | Brightfield, Rottermann Contrast, Unilateral or Bilateral Darkfield |
| Field Diameter | 65 mm |
| Cooling | Passive (max. +6°C above ambient) |
| Software Integration | Fully encoded |
| Compliance | Designed for GLP/GMP-aligned workflows |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TL3000 ST |
| Illumination Type | Halogen Transmitted Light |
| Optical Design | Multi-layer Coated Optics |
| Contrast Control | Adjustable Sliding Mirror |
| Vibration Damping | Integrated Anti-Vibration Pads |
| Working Area | Large Format Stage Platform |
| Color Temperature Enhancement | Built-in Daylight Simulation (No External Filter Required) |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TL4000 BFDF |
| Illumination Modes | Brightfield & Darkfield |
| Working Area | Large Format (≥150 × 120 mm) |
| Vibration Damping | Integrated Anti-Vibration Elastomeric Feet |
| Optional Stage | Motorized or Manual XY Slide-on Stage with Focusing Compatibility |
| Compliance | CE, ISO 9001 Manufacturing Environment |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TL4000 RC |
| Illumination Technology | Rottermann Contrast (RC) |
| Optical Compatibility | Designed for Leica M-series and Z-series stereo microscopes |
| Mechanical Stage Integration | Slide-on XY mechanical stage with focus-synchronized movement |
| Vibration Damping | Integrated high-performance anti-vibration pads |
| Regulatory Compliance | CE-marked, compliant with IEC 61000-6-3 (EMC) and IEC 61000-6-2 (immunity) |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TL4000 RCI |
| Illumination Technology | Rottermann Contrast (localized differential interference contrast via oblique transmitted lighting) |
| Interface | Dual USB 2.0 for brightness control and device communication |
| Mirror Options | Adjustable planar and concave reflectors for dynamic positive/negative relief contrast |
| Stage Integration | Slide-on mechanical stage compatible with transmitted-light focusing |
| Color Temperature Management | Constant Color Intensity Control (CCIC) — intensity adjustment without white balance recalibration |
| Vibration Damping | Integrated elastomeric anti-vibration feet |
| Remote Operation | Software-controllable illumination, automated image acquisition, and time-lapse sequencing |
| Compliance | Designed for integration into Leica Z6 APO, M205 FA, and other modular stereo microscope systems per DIN EN ISO 9001 manufacturing standards |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | TL5000 Ergo |
| Illumination Type | High-Uniformity White LED |
| Field Diameter | 65 mm |
| Contrast Modes | Optimized Rottermann Contrast, Low-Reflection Darkfield, Uniform Brightfield |
| Automation | Motorized Aperture Synchronized with Zoom Position |
| Software Integration | Fully Encoded & Compatible with Leica LAS / LAS AF |
| Ergonomic Design | Flat, Low-Profile Platform for Fatigue-Free Operation |
| Compliance | Designed for GLP/GMP-Lab Environments, Supports Audit-Trail-Capable Workflow in LAS AF |
| Brand | Leica |
|---|---|
| Origin | Germany |
| Model | UC Enuity |
| Type | Ultramicrotome for Electron Microscopy Sample Preparation |
| Temperature Control | Integrated Cryo Chamber with Precise Thermal Regulation (Room Temp to −160 °C) |
| Automation | Auto-alignment of Block Face and Knife, Automated Trimming, Fluorescence-Guided Targeting |
| Compatibility | Diamond/Knife Knives, Glass Knives, Silicon Wafers & EM Grids |
| Ergonomics | Fully Adjustable Stereo Microscope Height & Angle, Padded Arm Supports, UV-Blocking Safety Shield |
| Connectivity | RemoteCare™ Diagnostic Platform with Real-time Parameter Monitoring & Error Code Reporting |
| Compliance | Designed for GLP/GMP-adjacent workflows |
