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| Brand | SCIEX |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | API 4000 Q-Trap |
| Instrument Type | Triple Quadrupole Linear Ion Trap Hybrid |
| Mass Range | 5–2000 m/z |
| Sensitivity | <10 fg on-column for SRM (e.g., reserpine) |
| Resolution | Unit mass resolution (0.7 Da full width at half maximum) |
| Accurate Mass Capability | Not applicable (nominal mass instrument) |
| Ion Source Options | TurboIonSpray® and APCI® with plug-and-play interchangeability |
| Collision Cell | LINAC™ high-efficiency linear accelerator collision cell |
| Detection System | Pulse-counting electron multiplier |
| Dynamic Range | 1–4 × 10⁶ cps |
| Vacuum System | Dual-stage turbomolecular pumps with air-cooled design |
| Operating Temperature | 15–30 °C |
| Power Supply | 208–240 V AC, 50/60 Hz |
| Required Gases | High-purity nitrogen (≥99.999%), zero-air (oil-free, particle-free compressed air) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | API 3000 |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Mass Range | 10–3000 Da |
| Sensitivity | S/N ≥ 100:1 for 1 pg on-column reserpine (ESI+) |
| Resolution | 0.5–0.7 Da (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Ion Sources | Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) |
| Operating Temperature | 15–30 °C |
| Power Supply | 208–240 V AC, 50/60 Hz |
| Required Gases | High-purity nitrogen (≥99.999%), zero-air (oil-free, particle-filtered compressed air) |
| Vacuum System | Varian DS602 dual-stage rotary vane pump with oil mist filter |
| Brand | Waters |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Model | Xevo TQ-S |
| Configuration | Refurbished System with Full Functional Validation |
| Ionization Compatibility | Electrospray (ESI), Atmospheric Pressure Chemical Ionization (APCI), and Optional Sources (e.g., APPI, ESCi) |
| Mass Analyzer Architecture | Three Sequential Quadrupole Stages (Q1 → Collision Cell → Q3) |
| Scan Modes | MRM, Full Scan, Product Ion Scan, Precursor Ion Scan, Neutral Loss Scan, Selected Reaction Monitoring (SRM), RADAR™ Simultaneous Quantitation & Screening |
| Software Platform | MassLynx v4.2 or Later with TargetLynx XS, QuanLynx, and UNIFI Integration Capabilities |
| Regulatory Compliance Support | 21 CFR Part 11 Audit Trail, Electronic Signatures, GLP/GMP Data Integrity Framework |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (for reserpine, ESI+) |
| Resolution | Full Width at Half Maximum (FWHM) 0.5–0.7 m/z |
| Mass Accuracy | ±0.1 Da (internal calibration) |
| Configuration | Used / Refurbished System with HPLC Integration Capability |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | API4000 Q-Trap |
| Instrument Type | Hybrid Triple Quadrupole/Linear Ion Trap Mass Spectrometer |
| Mass Range | 5–2,000 m/z |
| Sensitivity | <10 fg on-column for reserpine (MRM, ESI+) |
| Resolution | Unit mass resolution in Q1 and Q3 |
| Mass Accuracy | ±0.2 Da (calibrated) |
| Scan Speed | Up to 6,000 Da/sec |
| Dynamic Range | 4 orders of magnitude (1–4 × 10⁶ cps) |
| Vacuum System | Dual-stage air-cooled turbomolecular pumps |
| Operating Temperature | 15–30 °C |
| Power Supply | 208–240 V AC, 50/60 Hz |
| Required Gases | High-purity nitrogen (≥99.999%), zero-air (oil-free, particle- and hydrocarbon-free compressed air) |
| Brand | Agilent Technologies |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | 1100-1956 |
| Instrument Type | Single Quadrupole |
| Mass Range | 10–3000 amu |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 m/z (FWHM) |
| Mass Accuracy | ±0.1 Da (typical, calibrated) |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Xevo TQD |
| Instrument Type | Tandem Quadrupole (QqQ) |
| Mass Range | 10–3000 Da |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 Da (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Xevo TQ-S |
| Instrument Type | Tandem Quadrupole Mass Spectrometer |
| Ionization Compatibility | Electrospray Ionization (ESI), Atmospheric Pressure Chemical Ionization (APCI), and Optional Sources (e.g., ESCi, UniSpray) |
| Key Technology | StepWave™ Ion Optics, ScanWave™ Collision Cell, RADAR™ Acquisition Mode |
| Regulatory Alignment | Designed for GLP/GMP environments |
| Brand | Shimadzu |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | LCMS-2010EV |
| Instrument Type | Single Quadrupole |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 m/z (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Scan Speed | Up to 6000 amu/sec |
| Ionization Modes | ESI±, APCI± (optional) |
| Polarity Switching | Simultaneous positive/negative ion acquisition |
| Acquisition Modes | Full Scan, SIM, CID, Multi-Sequential Analysis (up to 64 methods per run) |
| Brand | Thermo Fisher |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Model | TSQ Quantum Ultra |
| Configuration | Refurbished & Fully Qualified System |
| Regulatory Compliance | Designed for GLP/GMP environments |
| Software Platform | Xcalibur 2.0.x or later with Tune 2.0.x |
| Brand | Shimadzu |
|---|---|
| Origin | Japan |
| Model | LCMS-8045 |
| Instrument Type | Triple Quadrupole (TQ) |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 m/z (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Polarity Switching Time | 5 ms |
| Scan Speed | 30,000 u/sec |
| Step Size | 0.1 u |
| Brand | Waters |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Model | TQD |
| Configuration | Integrated UPLC/MS/MS System |
| Ionization Options | Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) |
| Mass Range | 50–1200 m/z |
| Typical MRM Sensitivity | <10 fg on-column for reserpine (S/N ≥ 20:1) |
| Scan Speed | Up to 8,000 Da/sec in MRM mode |
| Collision Cell | T-Wave™ RF-only quadrupole collision cell |
| Data Acquisition Rate | ≥20 MRM transitions/sec |
| Software Platform | MassLynx v4.1 with TargetLynx, QuanLynx, QCMonitor, RADAR, TrendPlot, InliStart, and Quanpedia modules |
| Compliance | Fully compatible with 21 CFR Part 11 audit trail requirements and GLP/GMP workflows |
| Brand | Thermo Fisher |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Import Status | Imported |
| Model | TSQ Quantum Access MAX |
| Instrument Type | Triple Quadrupole (TQ) |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 m/z (FWHM) |
| Mass Accuracy | ≤ 0.1 Da (external calibration) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | SCIEX 5500 |
| Instrument Type | Triple Quadrupole Mass Spectrometer |
| Configuration | Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) |
| Mass Range | m/z 5–2000 (typical for QqQ operation) |
| Polarity Switching Speed | ≤ 50 ms |
| MRM Dwell Time | down to 1 ms |
| Ion Source Options | Turbo V™, DuoSpray™, PhotoSpray™ |
| Ion Guide | QJet™ 2 Collision Cell |
| Software Platform | Analyst® 1.7.1 or later |
| Regulatory Compliance | Designed for 21 CFR Part 11–compliant workflows (audit trail, electronic signatures, user access control) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | API 4000 |
| Instrument Type | Tandem Quadrupole (QqQ) |
| Ionization Modes | Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) |
| Software Platform | Analyst® 1.6.3 or later |
| Regulatory Compliance | Designed for GLP/GMP environments |
| Mass Range | m/z 5–3,000 (typical operational range) |
| Sensitivity | Sub-femtogram on-column detection for selected pharmaceutical compounds (e.g., ≤5 fg on-column for midazolam in MRM mode) |
| Resolution | Unit mass resolution (0.7 Da full width at half maximum, FWHM) |
| Mass Accuracy | ±0.2 Da (calibrated) |
| Brand | Agilent Technologies |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole (QQQ) |
| Model | LC-MS 1200-6410 |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 m/z (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Flow Rate Compatibility | 0.1–2.5 mL/min |
| Ion Source | Jet Stream Electrospray Ionization (ESI) |
| Optional Ion Sources | APCI, APPI |
| Software | MassHunter Workstation (Enhanced QQQ Edition) |
| Brand | Waters |
|---|---|
| Origin | USA |
| Instrument Type | Tandem Quadrupole (QqQ) LC-MS/MS |
| Model | Xevo TQD |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 m/z (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Configuration | Includes UPLC Binary Solvent Manager, Sample Manager, Sample Organizer, CH-A Column Heater, E2M28 Vacuum Pump, SB-C18 Column (50 mm × 2.1 mm, 1.8 µm), MassLynx Software Suite (InliStart, Quanpedia, QCMonitor, TargetLynx, TrendPlot), and RADAR™ Acquisition Mode |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | Triple Quad 5500 |
| Instrument Type | Tandem Quadrupole (QqQ) LC-MS/MS |
| Ionization Sources | Turbo V, DuoSpray, PhotoSpray |
| Key Technology | eQ Electronics (50 ms polarity switching) |
| Software | Analyst® 1.7 or later |
| Compliance | Designed for GLP/GMP environments |
| Dimensions | 114 cm × 81 cm × 76 cm (W × D × H) |
| Weight | ~350 kg |
| Brand | Shimadzu |
|---|---|
| Origin | Japan |
| Model | LCMS-8080 |
| Instrument Type | Triple Quadrupole (TQ) |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 m/z (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Configuration | LC-MS/MS system with heated electrospray ionization (HESI) source |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | AB-4000 |
| Instrument Type | Triple Quadrupole (QqQ) |
| Mass Range | 5–2,000 m/z |
| Sensitivity | <10 fg on-column for reserpine (ESI+, 400 µL/min) |
| Resolution | Unit mass resolution (±0.13 u at full width at half maximum) |
| Accurate Mass Capability | ±0.13 u (calibrated, external standard) |
| Ionization Sources | Turbo V™ ESI/APCI dual-mode source with rapid switchable probe |
| Collision Cell | Linear Accelerator (LINAC™) collision cell |
| Detector | Digital Pulse Detection System with >5-decade dynamic range |
| Software | Analyst® 1.7.2 or later (21 CFR Part 11 compliant) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | AB API 4000 |
| Instrument Type | Triple Quadrupole (QqQ) with Linear Accelerator (LINAC) Collision Cell |
| Mass Range | 10–3000 Da |
| Sensitivity | S/N ≥ 100:1 for 1 pg on-column reserpine (ESI+) |
| Resolution | 0.5–0.7 Da (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Ionization Sources | TurboIonSpray® and APCI® (plug-and-play interchangeable probes) |
| Vacuum System | Dual-stage air-cooled turbomolecular pumps |
| Dimensions (H×D×L) | 52 × 50 × 130 cm |
| Operating Environment | 15–30 °C, 208–240 V AC, High-Purity Nitrogen & Zero-Air |
| Brand | Thermo Fisher |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Model | TSQ Quantum Ultra |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, SRM mode) |
| Resolution | 0.5–0.7 m/z (FWHM) |
| Mass Accuracy | ±0.1 Da (typical under calibrated conditions) |
| Configuration | Refurbished, fully validated, factory-reconditioned system with dual ESI/APCI source |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole / Linear Ion Trap Hybrid System |
| Model | 3200 Q-TRAP |
| Mass Range | 5–2,000 m/z (typical operational range) |
| Sensitivity | Sub-pg on-column for small molecules (e.g., <10 fg injected for reserpine S/N ≥ 50:1 in MRM) |
| Resolution | Unit mass resolution in both Q1 and Q3 |
| Accurate Mass Capability | Not applicable (non-high-resolution system) |
| Brand | Thermo Fisher |
|---|---|
| Origin | USA |
| Instrument Type | Tandem Quadrupole (Triple Quadrupole) |
| Mass Range | m/z 10–3000 |
| Quantitative Capability | Up to 3000 Timed-SRMs per run |
| Polarity Switching Time | ≤25 ms |
| H-SRM Dwell Time | 2 ms |
| Ion Source | Thermo Scientific Ion Max with HESI-II Probe |
| Software | Thermo Scientific TraceFinder and/or QuanBrowser (v5.0+) |
| Compliance | Designed for GLP/GMP environments |
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