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| Brand | BI/Biosensing Instrument |
|---|---|
| Origin | USA |
| Model | BI-4500 |
| Detection Principle | Surface Plasmon Resonance (SPR) |
| Optical Wavelength | 670 nm |
| Angular Resolution | <0.01 mDeg RMS |
| Sensitivity | <0.06 RU RMS |
| Flow Channels | 5 independent microfluidic channels |
| Flow Rate Range | 1.0–250 µL/min |
| Minimum Analyte MW | 100 Da |
| Injection Volume | >50 µL |
| Injection Time | <0.2 s |
| Liquid-Phase Incident Angle Range | 67–81° |
| Gas-Phase Incident Angle Range (optional) | 40–47° |
| BI-DirectFlow™ Technology | Yes |
| Software Compliance | FDA 21 CFR Part 11 ready (audit trail, electronic signature support), GLP/GMP-compatible data handling |
| Origin | USA |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | BI-4500 |
| Price Range | USD 70,000 – 140,000 |
| Sample Flow Channels | 5 |
| Light Source | Dual 670 nm LEDs |
| Detection Speed | 4 ms |
| Incident Angle Range | 40–47° (gas phase), 67–81° (liquid phase) |
| Sensitivity | < 0.06 RU RMS (0.01 mdeg RMS) |
| Drift | ≤ 1 RU/hour (≤ 0.17 mdeg/hour) under ambient temperature drift < 1 °C/hour |
| Interface | USB 3.0 |
| Dimensions | 355 × 250 × 515 mm (W × H × D) |
| Weight | 11.5 kg |
| Origin | USA |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | BI-2500 |
| Detection Range | <100 Da, KD = 10⁻³ M (1 mM) to 10⁻¹² M (1 pM), angular resolution <10⁻⁴° |
| Sample Channels | 3 |
| Injection Volume | >50 µL |
| Analysis Time Scale | milliseconds to hours (kinetically resolved) |
| Temperature Control | Ambient only |
| Brand | Biosensing Instrument |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Instrument Type | Surface Plasmon Resonance (SPR) |
| Model | SPRm 200 |
| Detection Range | 200 Da |
| Channel Configuration | 5 parallel microfluidic channels |
| Sample Throughput | 384 × 2 (dual-layer microarray format) |
| Injection Volume | 1–1500 µL (application-dependent) |
| Assay Duration | Millisecond to hour-scale (kinetically resolved) |
| Temperature Control Range | 15–40 °C |
| Detection Mode | Simultaneous SPR imaging + brightfield optical microscopy |
| Spatial Resolution | Pixel-level SPR signal mapping (< 2 µm pixel pitch) |
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